REEP3 Antibody, Biotin conjugated

Code CSB-PA754137LD01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) REEP3 Polyclonal antibody
Uniprot No.
Target Names
REEP3
Alternative Names
REEP3; C10orf74; Receptor expression-enhancing protein 3
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Receptor expression-enhancing protein 3 protein (80-255AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Biotin
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Microtubule-binding protein required to ensure proper cell division and nuclear envelope reassembly by sequestering the endoplasmic reticulum away from chromosomes during mitosis. Probably acts by clearing the endoplasmic reticulum membrane from metaphase chromosomes.
Gene References into Functions
  1. Our results show that REEP3/4 function redundantly to clear the endoplasmic reticulum from metaphase chromatin, thereby ensuring correct progression through mitosis and proper nuclear envelope architecture. PMID: 23911198
  2. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) PMID: 20379614
  3. Receptor Expression-Enhancing Proteins (REEP) 3 is one of the six human homologs of yeast Yop1p, a probable regulator of cellular vesicle trafficking between the endoplasmatic reticulum and the Golgi network. Positional candidate gene for autism. PMID: 17290275
  4. Observational study of gene-disease association. (HuGE Navigator) PMID: 16385451
  5. Observational study, meta-analysis, and genome-wide association study of gene-disease association. (HuGE Navigator) PMID: 18940312

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Subcellular Location
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein Families
DP1 family
Tissue Specificity
Expressed in circumvallate papillae.
Database Links

HGNC: 23711

OMIM: 609348

KEGG: hsa:221035

STRING: 9606.ENSP00000362863

UniGene: Hs.499833

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