RELT Antibody, Biotin conjugated

Code CSB-PA08179D0Rb
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) RELT Polyclonal antibody
Uniprot No.
Target Names
RELT
Alternative Names
Receptor expressed in lymphoid tissues antibody; Relt antibody; TNFRSF19L antibody; TR19L_HUMAN antibody; Tumor necrosis factor receptor superfamily member 19L antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Tumor necrosis factor receptor superfamily member 19L protein (26-153AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Biotin
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
May play a role in apoptosis. Induces activation of MAPK14/p38 and MAPK8/JNK MAPK cascades, when overexpressed. Involved in dental enamel formation.
Gene References into Functions
  1. Collectively, this study provides more insights into RELT expression, RELT family member function, and the mechanism of RELT-induced death. PMID: 28688764
  2. report that overexpression of RELT or its homologues RELL1 and RELL2 in HEK 293 epithelial cells results in cell death with morphological characteristics consistent with the activation of an apoptotic pathway. PMID: 19969290
  3. Receptor expressed in lymphoid tissue (RELT) and its novel homologues RELL1 and RELL2 co-localize with one another at the plasma membrane. PMID: 16389068
Subcellular Location
Cell membrane; Single-pass type I membrane protein. Cytoplasm. Cytoplasm, perinuclear region.
Protein Families
RELT family
Tissue Specificity
Spleen, lymph node, brain, breast and peripheral blood leukocytes (at protein level). Expressed highly in bone marrow and fetal liver. Very low levels in skeletal muscle, testis and colon. Not detected in kidney and pancreas.
Database Links

HGNC: 13764

OMIM: 611211

KEGG: hsa:84957

STRING: 9606.ENSP00000064780

UniGene: Hs.533720

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