REM1 Antibody

Datasheet

Code	CSB-PA019559LA01HU
Size	US$166
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Image	Immunofluorescence staining of HepG2 cells with CSB-PA019559LA01HU at 1:133, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) REM1 Polyclonal antibody

Uniprot No.

O75628

Target Names

REM1

Alternative Names

E030011C07Rik antibody; GD:REM antibody; GES antibody; GTP binding protein REM antibody; GTP binding protein REM 1 antibody; GTP binding protein REM1 antibody; GTP-binding protein REM 1 antibody; GTPase GES antibody; GTPase regulating endothelial cell sprouting antibody; GTPase-regulating endothelial cell sprouting antibody; MGC114556 antibody; MGC48669 antibody; OTTMUSP00000016855 antibody; Rad and Gem like GTP binding protein 1 antibody; Rad and Gem-like GTP-binding protein 1 antibody; RAS (RAD and GEM) like GTP binding antibody; RAS like GTP binding antibody; RAS like GTP binding protein REM antibody; REM 1 antibody; Rem1 antibody; REM1_HUMAN antibody; RP23-35I8.9 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human GTP-binding protein REM 1 protein (2-153AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The REM1 Antibody (Product code: CSB-PA019559LA01HU) is Non-conjugated. For REM1 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA019559LB01HU	REM1 Antibody, HRP conjugated	ELISA
FITC	CSB-PA019559LC01HU	REM1 Antibody, FITC conjugated
Biotin	CSB-PA019559LD01HU	REM1 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, IF

Recommended Dilution

Application	Recommended Dilution
IF	1:50-1:200

Protocols

ELISA Protocol
Immunofluorescence (IF) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Promotes endothelial cell sprouting and actin cytoskeletal reorganization. May be involved in angiogenesis. May function in Ca(2+) signaling.

Gene References into Functions

We conclude that Rem is capable of regulating L-type current, that release of Rem block is modulated by cellular kinase pathways, and that the Ca(V)1.2 COOH terminus contributes to Rem-dependent channel inhibition. PMID: 16648185
a role for the Rem C terminus in plasma membrane localization through association with phosphatidylinositol lipids. PMID: 17686775

Protein Families

Small GTPase superfamily, RGK family

Tissue Specificity

Most highly expressed in the endothelial lining of the blood vessels in uterus and heart. Lower levels found in spleen, lymph node, kidney and testis. Also found in cells with secretory function such as the islets of Langerhans, lobule/duct epithelium in

Database Links

HGNC: 15922

OMIM: 610388

KEGG: hsa:28954

STRING: 9606.ENSP00000201979

UniGene: Hs.247729

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Protein Service

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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