RER1 Antibody

Code CSB-PA019567LA01HU
Size US$166
Order now
Image
  • Immunohistochemistry of paraffin-embedded human gastric cancer using CSB-PA019567LA01HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human endometrial cancer using CSB-PA019567LA01HU at dilution of 1:100

  • Immunofluorescent analysis of 293T cells using CSB-PA019567LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

The Latest Promotion Free Antibody trial simple
Have Questions? Leave a Message or Start an on-line Chat

Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) RER1 Polyclonal antibody
Uniprot No.
Target Names
RER1
Alternative Names
RER1; Protein RER1
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Protein RER1 protein (85-139AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The RER1 Antibody (Product code: CSB-PA019567LA01HU) is Non-conjugated. For RER1 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA019567LB01HU RER1 Antibody, HRP conjugated ELISA
FITC CSB-PA019567LC01HU RER1 Antibody, FITC conjugated
Biotin CSB-PA019567LD01HU RER1 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, IHC, IF
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
IF 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

 Customer Reviews

There are currently no reviews for this product.

Submit a Review here

Target Background

Function
Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment.
Gene References into Functions
  1. RER1 is a novel and potential important mediator of elevated alphaSyn levels PMID: 28877262
  2. Rer1p regulates the ER retention of immature or misfolded rhodopsin and modulates its intracellular trafficking through the early secretory pathway. PMID: 25096327
  3. Charcot-Marie-Tooth disease-related PMP22 is trapped in the endoplasmic reticulum by calnexin-dependent retention and Rer1-mediated early Golgi retrieval systems and partly degraded by the Hrd1-mediated endoplasmic reticulum-associated degradation system. PMID: 25385046
  4. Rer1p depletion reduced ciliary length and function by increasing gamma-secretase complex assembly and activity and, consequently, enhancing Notch signaling as well as reducing Foxj1a expression. PMID: 23479743
  5. Synoviolin up-regulates amyloid beta production by targeting a negative regulator of gamma-secretase, Rer1, for degradation. PMID: 23129766
  6. RER1 modulates amyloid-beta production by altering trafficking of gamma-secretase and amyloid precursor protein. PMID: 23043097
  7. Downregulation of Rer1 leads to increased surface localization of Pen2, whereas overexpression of Rer1 stabilizes unassembled Pen2. Rer1 is the first identified interaction partner of mammalian transmembrane-based retention/retrieval signals. PMID: 17668005

Show More

Hide All

Subcellular Location
Golgi apparatus membrane; Multi-pass membrane protein.
Protein Families
RER1 family
Database Links

HGNC: 30309

KEGG: hsa:11079

STRING: 9606.ENSP00000302088

UniGene: Hs.525527

icon of phone
Call us
301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
icon of address
Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
icon of social media
Join us with

Subscribe newsletter

Leave a message

* To protect against spam, please pass the CAPTCHA test below.
CAPTCHA verification
© 2007-2024 CUSABIO TECHNOLOGY LLC All rights reserved. 鄂ICP备15011166号-1
Place an order now

I. Product details

*
*
*
*

II. Contact details

*
*

III. Ship To

*
*
*
*
*
*
*

IV. Bill To

*
*
*
*
*
*
*
*