RFC4 Antibody, Biotin conjugated

Code CSB-PA019591LD01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) RFC4 Polyclonal antibody
Uniprot No.
Target Names
RFC4
Alternative Names
A1 37 antibody; A1 37 kDa subunit antibody; Activator 1 37 antibody; Activator 1 37 kDa subunit antibody; Activator 1 subunit 4 antibody; Replication factor C 37 antibody; Replication factor C 37 kDa subunit antibody; Replication factor C subunit 4 antibody; Replication factor C4 antibody; RF-C 37 kDa subunit antibody; RFC 37 antibody; RFC37 antibody; RFC4 replication factor C (activator 1)4 37kDa antibody; RfC4 antibody; RFC4_HUMAN antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Replication factor C subunit 4 protein (9-142AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Biotin
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins proliferating cell nuclear antigen (PCNA) and activator 1. This subunit may be involved in the elongation of the multiprimed DNA template.
Gene References into Functions
  1. Expression level of RFC4 was up regulated in cervical squamous cell carcinoma. PMID: 28341182
  2. RFC4 is frequently overexpressed in CRC, and is associated with tumor progression and worse survival outcome. This might be attributed to the regulation of CRC cell proliferation and cell cycle arrest by RFC4 PMID: 25407051
  3. The knockdown of endogenous replication factor C4 decreases the growth and enhances the chemosensitivity of hepatocellular carcinoma cells. PMID: 18492021
Subcellular Location
Nucleus.
Protein Families
Activator 1 small subunits family
Database Links

HGNC: 9972

OMIM: 102577

KEGG: hsa:5984

STRING: 9606.ENSP00000296273

UniGene: Hs.732098

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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