RGS18 Antibody, FITC conjugated

Code CSB-PA019649LC01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) RGS18 Polyclonal antibody
Uniprot No.
Target Names
RGS18
Alternative Names
Regulator of G protein signalling 13 antibody; Regulator of G Protein Signalling 18 antibody; Regulator of G-protein signaling 18 antibody; RGS 18 antibody; RGS13 antibody; RGS18 antibody; RGS18_HUMAN antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Regulator of G-protein signaling 18 protein (28-84AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
FITC
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G(i) alpha-1, G(i) alpha-2, G(i) alpha-3 and G(q) alpha.
Gene References into Functions
  1. These findings indicate cross-talk between platelet activation and inhibition pathways at the level of RGS18 and Gq. PMID: 22234696
  2. Data show that that SPL/RGS/SHP1 complexes are present in resting platelets where constitutive phosphorylation of SPL(Y398) creates an atypical binding site for SHP-1. PMID: 22210881
  3. molecular cloning and characterization of RGS18 as a regulator of G protein signalling in human platelets PMID: 11955952
  4. gene mapped to chromosome 1. PMID: 16484797
Subcellular Location
Cytoplasm.
Tissue Specificity
Expressed in peripheral leukocytes, bone marrow, platelet, spleen and fetal liver.
Database Links

HGNC: 14261

OMIM: 607192

KEGG: hsa:64407

STRING: 9606.ENSP00000356430

UniGene: Hs.440890

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