RHEBL1 Antibody

Code CSB-PA855034LA01HU
Size US$166
Order now
Image
  • Immunohistochemistry of paraffin-embedded human ovarian cancer using CSB-PA855034LA01HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human appendix tissue using CSB-PA855034LA01HU at dilution of 1:100

The Latest Promotion Free Antibody trial simple
Have Questions? Leave a Message or Start an on-line Chat

Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) RHEBL1 Polyclonal antibody
Uniprot No.
Target Names
RHEBL1
Alternative Names
RHEBL1 antibody; GTPase RhebL1 antibody; Ras homolog enriched in brain like-1 c antibody; RhebL1c antibody; Ras homolog enriched in brain-like protein 1 antibody; Rheb-like protein 1 antibody; Rheb2 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human GTPase RhebL1 protein (1-180AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The RHEBL1 Antibody (Product code: CSB-PA855034LA01HU) is Non-conjugated. For RHEBL1 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA855034LB01HU RHEBL1 Antibody, HRP conjugated ELISA
FITC CSB-PA855034LC01HU RHEBL1 Antibody, FITC conjugated
Biotin CSB-PA855034LD01HU RHEBL1 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, IHC
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

 Customer Reviews

There are currently no reviews for this product.

Submit a Review here

Target Background

Function
Binds GTP and exhibits intrinsic GTPase activity. May activate NF-kappa-B-mediated gene transcription. Promotes signal transduction through MTOR, activates RPS6KB1, and is a downstream target of the small GTPase-activating proteins TSC1 and TSC2.
Gene References into Functions
  1. High RHEBL1 expression is associated with lung cancer. PMID: 28209923
  2. These results establish CAD as a downstream effector of Rheb and suggest a possible role of Rheb in regulating de novo pyrimidine nucleotide synthesis.(Rheb small GTPases, which consist of Rheb1 and Rheb2 (also known as RhebL1) PMID: 25422319
  3. RhebL1 may be impacting the mTOR pathway in a different manner than Rheb1. PMID: 21655954
  4. Data show that Rheb like-1 protein (RhebL1) rescues mTOR signaling during nutrient withdrawal, and identify critical residues in Rheb and RhebL1 which are required for their efficient activation of mTOR signaling. PMID: 16098514
  5. RHEBL1 is a positive regulator of NF-kappa B-mediated gene transcription. PMID: 16328882

Show More

Hide All

Subcellular Location
Endomembrane system; Lipid-anchor; Cytoplasmic side. Cytoplasm.
Protein Families
Small GTPase superfamily, Rheb family
Tissue Specificity
Ubiquitously expressed. Expression increased at least 2-fold in several tumor cell lines.
Database Links

HGNC: 21166

KEGG: hsa:121268

STRING: 9606.ENSP00000301068

UniGene: Hs.159013

icon of phone
Call us
301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
icon of address
Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
icon of social media
Join us with

Subscribe newsletter

Leave a message

* To protect against spam, please pass the CAPTCHA test below.
CAPTCHA verification
© 2007-2024 CUSABIO TECHNOLOGY LLC All rights reserved. 鄂ICP备15011166号-1
Place an order now

I. Product details

*
*
*
*

II. Contact details

*
*

III. Ship To

*
*
*
*
*
*
*

IV. Bill To

*
*
*
*
*
*
*
*