RIMS2 Antibody

Datasheet

Code	CSB-PA892173LA01HU
Size	US$166
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Image	Immunofluorescent analysis of PC-3 cells using CSB-PA892173LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) RIMS2 Polyclonal antibody

Uniprot No.

Q9UQ26

Target Names

RIMS2

Alternative Names

KIAA0751 antibody; Non small cell lung cancer RimL3a protein antibody; Non small cell lung cancer RimL3c protein antibody; OBOE antibody; Protein regulating synaptic membrane exocytosis 2 antibody; Rab-3-interacting molecule 2 antibody; Rab-3-interacting protein 3 antibody; Rab3 interacting molecule 2 antibody; RAB3IP3 antibody; Regulating synaptic membrane exocytosis 2 antibody; Regulating synaptic membrane exocytosis protein 2 antibody; RIM 2 antibody; Rims2 (gene name) antibody; Rims2 antibody; RIMS2_HUMAN antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Regulating synaptic membrane exocytosis protein 2 protein (667-943AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The RIMS2 Antibody (Product code: CSB-PA892173LA01HU) is Non-conjugated. For RIMS2 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA892173LB01HU	RIMS2 Antibody, HRP conjugated	ELISA
FITC	CSB-PA892173LC01HU	RIMS2 Antibody, FITC conjugated
Biotin	CSB-PA892173LD01HU	RIMS2 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, IF

Recommended Dilution

Application	Recommended Dilution
IF	1:50-1:200

Protocols

ELISA Protocol
Immunofluorescence (IF) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

Rab effector involved in exocytosis. May act as scaffold protein. Plays a role in dendrite formation by melanocytes.

Gene References into Functions

Electrophysiological characterization of VDCC currents revealed that the suppressive effect of RIM2alpha on voltage-dependent inactivation (VDI) was stronger than that of RIM1alpha for the CaV2.1 variant containing the region encoded by exons 44 and 47. PMID: 28377503
Here, we report that, like Rab3A, RIM and Munc13 are present in human sperm and that they play a functional role in acrosomal exocytosis before the acrosomal calcium efflux PMID: 22248876
These data suggest that RIM2beta contributes to the stabilization of Ca(v)1.3 gating kinetics in immature cochlear inner hair cells. PMID: 20363327
Western blot analysis shows increased RIMS2 protein expression in the amygdala in schizophrenia. PMID: 18490030
tick-borne encephalitis virus -NS5 has high affinity to regulating synaptic membrane exocytosis-2 (RIMS2) and Scribble, whereas DENV-NS5 binds primarily to the tight junction protein zonula occludens-1 (ZO-1) PMID: 19199833

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Subcellular Location

Cell membrane; Peripheral membrane protein. Cell junction, synapse. Cell junction, synapse, presynaptic cell membrane; Peripheral membrane protein.

Tissue Specificity

Widely expressed. Expressed in melanocytes. In fetal tissues, predominantly expressed in the brain. In the retina, expressed in the outer plexiform layer (at protein level). In the cerebellum, expressed in Purkinje cells (at protein level). In the pancrea

Database Links

HGNC: 17283

OMIM: 606630

KEGG: hsa:9699

UniGene: Hs.655271

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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