RPS7 Antibody, HRP conjugated

Code CSB-PA020476LB01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) RPS7 Polyclonal antibody
Uniprot No.
Target Names
RPS7
Alternative Names
40S ribosomal protein S7 antibody; DBA8 antibody; Ribosomal protein S7 antibody; RPS 7 antibody; rps7 antibody; RS7_HUMAN antibody; S7 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human 40S ribosomal protein S7 protein (1-194AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
HRP
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Required for rRNA maturation.
Gene References into Functions
  1. BCCIPbeta interacts with the central basic region in S7 protein and regulates the extraribosomal distribution of S7. PMID: 28510697
  2. RPS7 role in cell proliferation in the context of Hepatitis B virus-related hepatocellular carcinoma.SIRT7 trans-represses RPS7 gene in the presence of HBx protein. PMID: 26442981
  3. Low expression of RPS7 is associated with colorectal cancer. PMID: 26735579
  4. Knockdown of RPS7 resulted in increased expression of P85alpha, P110alpha, and AKT2. PMID: 24244431
  5. The study found two ribosomal proteins, RPS7 and RPL13A that interact with the HMG (high-mobility group) box domain of SRY. PMID: 21114473
  6. S7 binds to MDM2, in vitro and in vivo, and the interaction between MDM2 and S7 leads to modulation of MDM2-p53 binding by forming a ternary complex among MDM2, p53 and S7. PMID: 17310983

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Involvement in disease
Diamond-Blackfan anemia 8 (DBA8)
Subcellular Location
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Protein Families
Eukaryotic ribosomal protein eS7 family
Database Links

HGNC: 10440

OMIM: 603658

KEGG: hsa:6201

STRING: 9606.ENSP00000339095

UniGene: Hs.534346

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