S100A13 Antibody

1. This is the first report for the association between HMGA1 and S100A13 expression in the modulation of thyroid cancer growth and invasion. PMID: 27008379
2. S100A13 interacts with the C2 domain of RAGE. PMID: 24982031
3. S100A13 is involved in cutaneous malignant melanoma resistance to DTIC/TMZ. PMID: 24722184
4. the IL1alpha-S100A13 tetrameric complex is the key complex formed during the non-classical pathway of IL1alpha release PMID: 21270123
5. S100A13 promotes the release of FGF-1 protein, but does not affect the transportation of FGF-1 protein in human umbilical vein endothelial cells. PMID: 20863990
6. S100A13 is expressed in melanocytic lesions when the angiogenic switch occurs and it may cooperate with VEGF-A in supporting the formation of new blood vessels, favoring the shift from radial to vertical tumor growth. PMID: 20208480
7. detected in both cells and fibers of the hippocampus at 12 weeks gestation, slightly stronger at 20 weeks, and then decreased with age. In the temporal cortex, strong in all cellular layers at 12 to 24 weeks, declined with age from 28 weeks onwards. PMID: 12645008
8. Stress-induced export of IL-1alpha involves the intracellular association with the Cu2+-binding protein, S100A13; the expression of a S100A13 mutant functions as a dominant-negative repressor of IL-1alpha release. PMID: 12746488
9. S100A13 protein translocation in response to extracellular S100 is mediated by receptor for advanced glycation endproducts in human endothelial cells PMID: 15033494
10. data show that the expression of endoglin and S100A13 protein corresponds to the activation of the endothelial cells in the process of endometriotic angiogenesis PMID: 15821778
11. In human astrocytic gliomas, S100A13 was significantly up-regulated in high-grade vascularized gliomas. Moreover, S100A13 expression significantly correlated with microvessel density and tumour grading. PMID: 16773219
12. Human S100A13 was heterologously expressed in Escherichia coli, purified and crystallized by the hanging-drop vapour-diffusion method. PMID: 17077500
13. S100A13 is a homodimer with four EF-hand motifs in an asymmetric unit, displaying a folding pattern similar to other S100 members. S100A13 has the unique structural feature with all alpha-helices being amphiphilic. PMID: 17374362
14. Despite the high similarity of the backbone conformation in each protomer, the crystal structures of human S100A13 at pH 7.5 and at pH 6.0 exhibit recognizable differences in the relative orientation of the protomers within the dimer PMID: 18259052

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HGNC: 10490

OMIM: 601989

KEGG: hsa:6284

STRING: 9606.ENSP00000344822

UniGene: Hs.516505