SAMD9L Antibody

Code CSB-PA095524
Size US$166
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Image
  • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA095524(SAMD9L Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200)
  • The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA095524(SAMD9L Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200)
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Product Details

Uniprot No.
Target Names
SAMD9L
Alternative Names
SAMD9L antibody; C7orf6 antibody; DRIF2 antibody; KIAA2005 antibody; UEF antibody; Sterile alpha motif domain-containing protein 9-like antibody; SAM domain-containing protein 9-like antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Synthetic peptide of Human SAMD9L
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
Antigen affinity purification
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
Liquid
Tested Applications
ELISA,IHC
Recommended Dilution
Application Recommended Dilution
ELISA 1:1000-1:2000
IHC 1:25-1:100
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
May be involved in endosome fusion. Mediates down-regulation of growth factor signaling via internalization of growth factor receptors.
Gene References into Functions
  1. Gain-of-function SAMD9L mutations cause a syndrome of cytopenia, immunodeficiency, MDS, and neurological symptoms in two unrelated Caucasian families. PMID: 28202457
  2. Missense Mutations in SAMD9L gene is Associated with Ataxia-Pancytopenia Syndrome. PMID: 27259050
  3. The findings highlight a novel tumor-suppressive role of SAMD9L inactivation by somatic mutation and decreased expression in human HBV-related HCC PMID: 25076857
Involvement in disease
Ataxia-pancytopenia syndrome (ATXPC)
Subcellular Location
Early endosome.
Tissue Specificity
Widely expressed in adult and fetal tissues. Variable expression in tumors. Down-regulated in breast cancer.
Database Links

HGNC: 1349

OMIM: 159550

KEGG: hsa:219285

STRING: 9606.ENSP00000326247

UniGene: Hs.489118

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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