SAMD9L Antibody

Code CSB-PA095524
Size US$166
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Image
  • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA095524(SAMD9L Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200)
  • The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA095524(SAMD9L Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200)
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Product Details

Uniprot No.
Target Names
SAMD9L
Alternative Names
SAMD9L antibody; C7orf6 antibody; DRIF2 antibody; KIAA2005 antibody; UEF antibody; Sterile alpha motif domain-containing protein 9-like antibody; SAM domain-containing protein 9-like antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Synthetic peptide of Human SAMD9L
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
Antigen affinity purification
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
Liquid
Tested Applications
ELISA,IHC
Recommended Dilution
Application Recommended Dilution
ELISA 1:1000-1:2000
IHC 1:25-1:100
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
May be involved in endosome fusion. Mediates down-regulation of growth factor signaling via internalization of growth factor receptors.
Gene References into Functions
  1. Gain-of-function SAMD9L mutations cause a syndrome of cytopenia, immunodeficiency, MDS, and neurological symptoms in two unrelated Caucasian families. PMID: 28202457
  2. Missense Mutations in SAMD9L gene is Associated with Ataxia-Pancytopenia Syndrome. PMID: 27259050
  3. The findings highlight a novel tumor-suppressive role of SAMD9L inactivation by somatic mutation and decreased expression in human HBV-related HCC PMID: 25076857
Involvement in disease
Ataxia-pancytopenia syndrome (ATXPC)
Subcellular Location
Early endosome.
Tissue Specificity
Widely expressed in adult and fetal tissues. Variable expression in tumors. Down-regulated in breast cancer.
Database Links

HGNC: 1349

OMIM: 159550

KEGG: hsa:219285

STRING: 9606.ENSP00000326247

UniGene: Hs.489118

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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