SCAMP5 Antibody

Datasheet

Code	CSB-PA855032LA01HU
Size	US$166
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Image	Immunohistochemistry of paraffin-embedded human adrenal gland tissue using CSB-PA855032LA01HU at dilution of 1:100 Immunofluorescent analysis of HepG2 cells using CSB-PA855032LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) SCAMP5 Polyclonal antibody

Uniprot No.

Q8TAC9

Target Names

SCAMP5

Alternative Names

SCAMP5; Secretory carrier-associated membrane protein 5; Secretory carrier membrane protein 5; hSCAMP5

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Secretory carrier-associated membrane protein 5 protein (170-235AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The SCAMP5 Antibody (Product code: CSB-PA855032LA01HU) is Non-conjugated. For SCAMP5 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA855032LB01HU	SCAMP5 Antibody, HRP conjugated	ELISA
FITC	CSB-PA855032LC01HU	SCAMP5 Antibody, FITC conjugated
Biotin	CSB-PA855032LD01HU	SCAMP5 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, IHC, IF

Recommended Dilution

Application	Recommended Dilution
IHC	1:20-1:200
IF	1:50-1:200

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

Required for the calcium-dependent exocytosis of signal sequence-containing cytokines such as CCL5. Probably acts in cooperation with the SNARE machinery. May play a role in accumulation of expanded polyglutamine (polyQ) protein huntingtin (HTT) in case of endoplasmic reticulum stress by inhibiting the endocytosis pathway.

Gene References into Functions

scanp5 is predicted to play a role in neuronal vesicle trafficking and be involed in autism PMID: 20071347
SCAMP5 is involved in calcium-regulated exocytosis of signal peptide-containing cytokines, in cooperation with the SNARE machinery of secretory vesicles. PMID: 19234194
exposure to ER stress increases SCAMP5 in the striatum, which positively regulates mtHTT aggregation via the endocytosis pathway PMID: 19240033

Subcellular Location

Cell membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein. Recycling endosome membrane; Multi-pass membrane protein. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein.

Protein Families

SCAMP family, SCAMP5 subfamily

Tissue Specificity

Expressed both by neuronal and non-neuronal tissues. Expressed in brain, stomach, thyroid, spinal cord, lymph node, trachea, adrenal gland, bone marrow and in the different parts of brain. In thyroid tissues, it is expressed by the follicular epithelial c

Database Links

HGNC: 30386

OMIM: 613766

KEGG: hsa:192683

STRING: 9606.ENSP00000355387

UniGene: Hs.374180

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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