SCAPER Antibody, Biotin conjugated

Code CSB-PA863150LD01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) SCAPER Polyclonal antibody
Uniprot No.
Target Names
SCAPER
Alternative Names
SCAPER antibody; KIAA1454 antibody; ZNF291 antibody; MSTP063 antibody; S phase cyclin A-associated protein in the endoplasmic reticulum antibody; S phase cyclin A-associated protein in the ER antibody; Zinc finger protein 291 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human S phase cyclin A-associated protein in the endoplasmic reticulum protein (1109-1400AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Biotin
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
CCNA2/CDK2 regulatory protein that transiently maintains CCNA2 in the cytoplasm.
Gene References into Functions
  1. An unstable [CCTG](n) repeat in the second intron of the ZNF291 gene, on chromosome 15q21-24, was identified. PMID: 17553665
  2. Study describes the biochemically purification and identification of SCAPER, a novel protein that specifically interacts with cyclin A/Cdk2 in vivo. PMID: 17698606
  3. By sequestering cyclin A/Cdk2, SCAPER is capable of directing the activity of this kinase complex away from the nucleus and regulating cyclin A/Cdk2 equilibrium in distinct subcellular compartments. PMID: 18245951
Subcellular Location
Endoplasmic reticulum. Nucleus. Note=Predominantly located in the endoplasmic reticulum, only a small portion is detected in the nucleus.
Tissue Specificity
Widely expressed with high expression in testis. Isoform 1 is detected in various tissues, including retina, fetal and adult brain. Isoform 2 is expressed in the retina at high levels, and in the brain at very low levels.
Database Links

HGNC: 13081

OMIM: 611611

KEGG: hsa:49855

STRING: 9606.ENSP00000326924

UniGene: Hs.458986

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