SCOC Antibody

Code CSB-PA020854LA01HU
Size US$166
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Image
  • Immunofluorescence staining of HepG2 cells with CSB-PA020854LA01HU at 1:266, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).

  • Immunohistochemistry of paraffin-embedded human heart tissue using CSB-PA020854LA01HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using CSB-PA020854LA01HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) SCOC Polyclonal antibody
Uniprot No.
Target Names
SCOC
Alternative Names
HRIHFB2072 antibody; Scoc antibody; SCOC_HUMAN antibody; SCOCO antibody; Short coiled coil protein antibody; Short coiled-coil protein antibody; UNC-69 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Short coiled-coil protein (1-121AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The SCOC Antibody (Product code: CSB-PA020854LA01HU) is Non-conjugated. For SCOC Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA020854LB01HU SCOC Antibody, HRP conjugated ELISA
FITC CSB-PA020854LC01HU SCOC Antibody, FITC conjugated
Biotin CSB-PA020854LD01HU SCOC Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, IHC, IF
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
IF 1:50-1:500
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Positive regulator of amino acid starvation-induced autophagy.
Gene References into Functions
  1. SCOC SNPs were associated with lifetime cannabis use, but the association did not reach genome-wide significance. [Meta-Analysis] PMID: 27023175
  2. SCOC forms a stable homogeneous complex with the coiled coil domain of FEZ1. SCOC dimerization and the SCOC surface residue R117 are important for this interaction. PMID: 24098481
  3. Studies indicate that FEZ1 (fasciculation and elongation protein zeta 1), SCOCO (short coiled-coil protein) and kinesins (kinesin heavy chain) are involved in biological transport process. PMID: 24116125
  4. The identification of SCOC and WAC as novel regulatory proteins with diverse functions in autophagy contributes towards a fuller understanding of autophagosome formation. PMID: 22354037
Subcellular Location
Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Golgi apparatus, trans-Golgi network. Cytoplasm, cytosol.
Protein Families
SCOC family
Tissue Specificity
Widely expressed with highest levels in brain, heart and skeletal muscle.
Database Links

HGNC: 20335

KEGG: hsa:60592

STRING: 9606.ENSP00000377751

UniGene: Hs.480815

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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