ENTR1 Antibody, Biotin conjugated

Code CSB-PA020897LD01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) ENTR1 Polyclonal antibody
Uniprot No.
Target Names
ENTR1
Alternative Names
ENTR1 antibody; SDCCAG3 antibody; Endosome-associated-trafficking regulator 1 antibody; Antigen NY-CO-3 antibody; Serologically defined colon cancer antigen 3 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Endosome-associated-trafficking regulator 1 protein (121-230AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Biotin
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Endosome-associated protein that plays a role in membrane receptor sorting, cytokinesis and ciliogenesis. Involved in the endosome-to-plasma membrane trafficking and recycling of SNX27-retromer-dependent cargo proteins, such as GLUT1. Involved in the regulation of cytokinesis; the function may involve PTPN13 and GIT1. Plays a role in the formation of cilia. Involved in cargo protein localization, such as PKD2, at primary cilia. Involved in the presentation of the tumor necrosis factor (TNF) receptor TNFRSF1A on the cell surface, and hence in the modulation of the TNF-induced apoptosis.
Gene References into Functions
  1. SDCCAG3 has a role in ciliogenesis and in localization of cargo to primary cilia PMID: 27767179
  2. The novel endosomal protein SDCCAG3 forms a complex with PTPN13 & interacts with GIT1. Interaction of SDCCAG3 with PTPN13 is mediated by the PTPN13 FERM domain & the SDCCAG3 N-terminus. SDCCAG3 expression levels are elevated in colon cancers. PMID: 23108400
  3. SDCCAG3 is important for protein trafficking and presentation of TNFR1 on the cell surface. PMID: 16332174
Subcellular Location
Cytoplasm. Early endosome. Endosome. Recycling endosome. Midbody. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, cilium basal body.
Protein Families
SDCCAG3 family
Tissue Specificity
Expressed in the colon (at protein level).
Database Links

HGNC: 10667

KEGG: hsa:10807

STRING: 9606.ENSP00000349929

UniGene: Hs.94300

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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