SEMA6B Antibody, FITC conjugated

Code CSB-PA862010LC01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) SEMA6B Polyclonal antibody
Uniprot No.
Target Names
SEMA6B
Alternative Names
SEM-SEMA-Y antibody; SEM6B_HUMAN antibody; sema domain; transmembrane domain (TM); and cytoplasmic domain; (semaphorin) 6B antibody; Sema Z antibody; SEMA-VIB antibody; Sema6b antibody; SEMAN antibody; semaphorin VIB antibody; Semaphorin-6B antibody; semaphorin-6Ba antibody; Semaphorin-Z antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Semaphorin-6B protein (756-888AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
FITC
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Functions as a cell surface repellent for mossy fibers of developping neurons in the hippocampus where it plays a role in axon guidance. May function through the PLXNA4 receptor expressed by mossy cell axons.; (Microbial infection) Acts as a receptor for P.sordellii toxin TcsL in the in the vascular endothelium.
Gene References into Functions
  1. Semaphorin 6B is related to tumour differentiation and metastasis in vivo, and tumour cell migration, adhesion and invasion in vitro. PMID: 23781008
  2. states a clear relation among breast cancer and SEMA6B expression; moreover we describe for the first time the SEMA6Ba protein and report here the analysis of SEMA6Ba RNA messenger, the protein expression and the cellular localization PMID: 23665584
  3. Gene SEMA6B is strongly down regulated by peroxisome proliferator-activated receptors. PMID: 15177567
Subcellular Location
Cell membrane; Single-pass type I membrane protein.
Protein Families
Semaphorin family
Tissue Specificity
Expressed in the brain in GABAergic neurons.
Database Links

HGNC: 10739

OMIM: 608873

KEGG: hsa:10501

STRING: 9606.ENSP00000301293

UniGene: Hs.465642

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