SFR1 Antibody

Code CSB-PA801256LA01HU
Size US$166
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Image
  • IHC image of CSB-PA801256LA01HU diluted at 1:200 and staining in paraffin-embedded human breast cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) SFR1 Polyclonal antibody
Uniprot No.
Target Names
SFR1
Alternative Names
SFR1 antibody; C10orf78 antibody; MEI5 antibody; MEIR5 antibody; Swi5-dependent recombination DNA repair protein 1 homolog antibody; Meiosis protein 5 homolog antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Swi5-dependent recombination DNA repair protein 1 homolog protein (5-93AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The SFR1 Antibody (Product code: CSB-PA801256LA01HU) is Non-conjugated. For SFR1 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA801256LB01HU SFR1 Antibody, HRP conjugated ELISA
FITC CSB-PA801256LC01HU SFR1 Antibody, FITC conjugated
Biotin CSB-PA801256LD01HU SFR1 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, IHC
Recommended Dilution
Application Recommended Dilution
IHC 1:200-1:500
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Component of the SWI5-SFR1 complex, a complex required for double-strand break repair via homologous recombination. Acts as a transcriptional modulator for ESR1.
Gene References into Functions
  1. SFR1 is a novel transcriptional modulator for ERalpha and a potential target in breast cancer therapy. PMID: 23874500
  2. that human SWI5-MEI5 has an evolutionarily conserved function in homologous recombination repair. PMID: 21252223
Subcellular Location
Nucleus.
Protein Families
SFR1/MEI5 family
Tissue Specificity
Widely expressed.
Database Links

HGNC: 29574

OMIM: 616527

KEGG: hsa:119392

STRING: 9606.ENSP00000358742

UniGene: Hs.93667

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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