SFR1 Antibody

Code CSB-PA801256LA01HU
Size US$166
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Image
  • IHC image of CSB-PA801256LA01HU diluted at 1:200 and staining in paraffin-embedded human breast cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) SFR1 Polyclonal antibody
Uniprot No.
Target Names
SFR1
Alternative Names
SFR1 antibody; C10orf78 antibody; MEI5 antibody; MEIR5 antibody; Swi5-dependent recombination DNA repair protein 1 homolog antibody; Meiosis protein 5 homolog antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Swi5-dependent recombination DNA repair protein 1 homolog protein (5-93AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The SFR1 Antibody (Product code: CSB-PA801256LA01HU) is Non-conjugated. For SFR1 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA801256LB01HU SFR1 Antibody, HRP conjugated ELISA
FITC CSB-PA801256LC01HU SFR1 Antibody, FITC conjugated
Biotin CSB-PA801256LD01HU SFR1 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, IHC
Recommended Dilution
Application Recommended Dilution
IHC 1:200-1:500
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Component of the SWI5-SFR1 complex, a complex required for double-strand break repair via homologous recombination. Acts as a transcriptional modulator for ESR1.
Gene References into Functions
  1. SFR1 is a novel transcriptional modulator for ERalpha and a potential target in breast cancer therapy. PMID: 23874500
  2. that human SWI5-MEI5 has an evolutionarily conserved function in homologous recombination repair. PMID: 21252223
Subcellular Location
Nucleus.
Protein Families
SFR1/MEI5 family
Tissue Specificity
Widely expressed.
Database Links

HGNC: 29574

OMIM: 616527

KEGG: hsa:119392

STRING: 9606.ENSP00000358742

UniGene: Hs.93667

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