SGCB Antibody, HRP conjugated

1. This study demonstrated that LGMD2E is the most common type of sarcoglycanopathies in the Iranian population. PMID: 28687063
2. Clinical severity of limb-girdle muscular dystrophy type 2Emay be predicted by SGCB gene mutation and sarcoglycan protein expression. PMID: 25862795
3. Defective assembly of sarcoglycan complex in patients with beta-sarcoglycan gene mutations PMID: 12060343
4. beta-sarcoglycan and SPATA18 may have a role in limb-girdle muscular dystrophy type 2E PMID: 16088906
5. While the quantity of beta-sarcoglycan was nearly normal in the limb girdle muscular dystrophy (LGMD)2E carrier, the levels of dysferlin protein were reduced to 50% of controls in the carriers of LGMD2B. PMID: 16934466
6. These data suggest that formation of the beta-delta-core may promote the export and deposition of sarcoglycan subcomplexes at the plasma membrane, and therefore identifies a mechanism for sarcoglycan transport. PMID: 17036316
7. The limb-girdle muscular dystrophy patients with beta-sarcoglycan deficient LGMD2E do not enable an accurate prediction of the genotype. PMID: 18996010

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HGNC: 10806

OMIM: 600900

KEGG: hsa:6443

STRING: 9606.ENSP00000370839

UniGene: Hs.438953