SH3BP2 Antibody

Datasheet
Code CSB-PA021224LA01HU
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Size US$299
Uniprot No. P78314
Image
  • IHC image of CSB-PA021224LA01HU diluted at 1:400 and staining in paraffin-embedded human pancreatic tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

Immunogen Recombinant Human SH3 domain-binding protein 2 protein (165-301AA)
Raised in Rabbit
Species Reactivity Human
Tested Applications ELISA, IHC; Recommended dilution: IHC:1:200-1:500
Relevance Binds differentially to the SH3 domains of certain proteins of signal transduction pathways. Binds to phosphatidylinositols; linking the hemopoietic tyrosine kinase fes to the cytoplasmic membrane in a phosphorylation dependent mechanism.
Form Liquid
Conjugate Non-conjugated
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method >95%, Protein G purified
Isotype IgG
Clonality Polyclonal
Alias SH3 domain-binding protein 2 (3BP-2), SH3BP2, 3BP2
Immunogen Species Homo sapiens (Human)
Protocols ELISA Protocol
Immunohistochemistry (IHC) Protocol
Research Area Signal Transduction
Target Names SH3BP2
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Binds differentially to the SH3 domains of certain proteins of signal transduction pathways. Binds to phosphatidylinositols; linking the hemopoietic tyrosine kinase fes to the cytoplasmic membrane in a phosphorylation dependent mechanism.
Involvement in disease Cherubism (CRBM)
Tissue Specificity Expressed in a variety of tissues including lung, liver, skeletal muscle, kidney and pancreas.
Database Links

HGNC: 10825

OMIM: 118400

KEGG: hsa:6452

STRING: 9606.ENSP00000422168

UniGene: Hs.167679

Pathway Natural killer cell mediated cytotoxicity

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