SH3GL3 Antibody

Code CSB-PA860359ESR1HU
Size US$166
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  • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA860359ESR1HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) SH3GL3 Polyclonal antibody
Uniprot No.
Target Names
SH3GL3
Alternative Names
CNSA3 antibody; EEN 2B L3 antibody; EEN B2 antibody; EEN-B2 antibody; EEN2BL3 antibody; EENB2 antibody; Endophilin 3 antibody; Endophilin A3 antibody; Endophilin-3 antibody; Endophilin-A3 antibody; H.sapiens mRNA for protein containing SH3 domain, SH3GL3 antibody; HsT19371 antibody; SH3 domain containing GRB2 like protein 3 antibody; SH3 domain GRB2 like 3 antibody; SH3 domain protein 2C antibody; SH3 domain-containing GRB2-like protein 3 antibody; SH3D2C antibody; SH3G3_HUMAN antibody; SH3GL3 antibody; SH3P13 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Endophilin-A3 protein (1-270AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form
Liquid
Tested Applications
ELISA, IHC
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Implicated in endocytosis. May recruit other proteins to membranes with high curvature.
Gene References into Functions
  1. Our findings indicate that SH3GL3 plays an important role in myeloma cell migration/invasion, stemness and chemo-resistance. The SH3GL3-mediated myeloma cell migration/invasion is mediated by FAK/PI3K signaling pathway. PMID: 27683032
  2. Aberrant DNA methylation of SH3GL3 gene is associated with colorectal cancer. PMID: 22901147
  3. SH3GL3 as a novel glioma invasion-associated candidate gene that likely contribute to the invasive phenotype of malignant gliomas. PMID: 21722156
  4. These data implicate ataxin-2 to play a role in endocytic receptor cycling.[Endophilin A3] PMID: 18602463
  5. importance of hapln1b and sh3gl3 in embryonic vascular development PMID: 19308258

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Subcellular Location
Cytoplasm. Early endosome membrane; Peripheral membrane protein.
Protein Families
Endophilin family
Tissue Specificity
Brain and testis.
Database Links

HGNC: 10832

OMIM: 603362

KEGG: hsa:6457

STRING: 9606.ENSP00000391372

UniGene: Hs.270055

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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