SH3GL3 Antibody

Datasheet

Code	CSB-PA860359ESR1HU
Size	US$166
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Image	Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA860359ESR1HU at dilution of 1:100
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Product Details
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Customer Reviews and Q&A
Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) SH3GL3 Polyclonal antibody

Uniprot No.

Q99963

Target Names

SH3GL3

Alternative Names

CNSA3 antibody; EEN 2B L3 antibody; EEN B2 antibody; EEN-B2 antibody; EEN2BL3 antibody; EENB2 antibody; Endophilin 3 antibody; Endophilin A3 antibody; Endophilin-3 antibody; Endophilin-A3 antibody; H.sapiens mRNA for protein containing SH3 domain, SH3GL3 antibody; HsT19371 antibody; SH3 domain containing GRB2 like protein 3 antibody; SH3 domain GRB2 like 3 antibody; SH3 domain protein 2C antibody; SH3 domain-containing GRB2-like protein 3 antibody; SH3D2C antibody; SH3G3_HUMAN antibody; SH3GL3 antibody; SH3P13 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Endophilin-A3 protein (1-270AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Tested Applications

ELISA, IHC

Recommended Dilution

Application	Recommended Dilution
IHC	1:20-1:200

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

■ Customer Reviews

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Target Background

Function

Implicated in endocytosis. May recruit other proteins to membranes with high curvature.

Gene References into Functions

Our findings indicate that SH3GL3 plays an important role in myeloma cell migration/invasion, stemness and chemo-resistance. The SH3GL3-mediated myeloma cell migration/invasion is mediated by FAK/PI3K signaling pathway. PMID: 27683032
Aberrant DNA methylation of SH3GL3 gene is associated with colorectal cancer. PMID: 22901147
SH3GL3 as a novel glioma invasion-associated candidate gene that likely contribute to the invasive phenotype of malignant gliomas. PMID: 21722156
These data implicate ataxin-2 to play a role in endocytic receptor cycling.[Endophilin A3] PMID: 18602463
importance of hapln1b and sh3gl3 in embryonic vascular development PMID: 19308258

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Subcellular Location

Cytoplasm. Early endosome membrane; Peripheral membrane protein.

Protein Families

Endophilin family

Tissue Specificity

Brain and testis.

Database Links

HGNC: 10832

OMIM: 603362

KEGG: hsa:6457

STRING: 9606.ENSP00000391372

UniGene: Hs.270055

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Email: [email protected]
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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Related pathways

Endocytosis

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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