SLC16A10 Antibody, HRP conjugated

Datasheet

Code	CSB-PA851563HB01HU
Size	US$166
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) SLC16A10 Polyclonal antibody

Uniprot No.

Q8TF71

Target Names

SLC16A10

Alternative Names

SLC16A10 antibody; MCT10 antibody; TAT1 antibody; Monocarboxylate transporter 10 antibody; MCT 10 antibody; Aromatic amino acid transporter 1 antibody; Solute carrier family 16 member 10 antibody; T-type amino acid transporter 1 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Monocarboxylate transporter 10 protein (159-201AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

HRP

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

Sodium-independent transporter that mediates the uptake of aromatic acids. Can function as a net efflux pathway for aromatic amino acids in the basosolateral epithelial cells.

Gene References into Functions

In the MCT10 modeled structure, N81 appeared to protrude into the putative trajectory of tryptophan. PMID: 28754537
the aim of this study was to examine if MCT8 and MCT10 increase the availability of triiodothyronine for its nuclear receptor. PMID: 27492966
High TAT1 expression is associated with metastasis and recurrence in endometrial cancer. PMID: 26779635
monocarboxylate transporter 10 facilitates bromoacetyl [(125)I] iodothyronine transport, but is not labeled by it PMID: 21315799
Increased MCT8 and decreased MCT10 expression within placentae of pregnancies complicated by IUGR may contribute to aberrant development of the fetoplacental unit. PMID: 20167367
MCT10 is at least as active a thyroid hormone transporter as hMCT8, and that both transporters facilitate iodothyronine uptake as well as efflux. PMID: 18337592

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Subcellular Location

Cell membrane; Multi-pass membrane protein. Basolateral cell membrane.

Protein Families

Major facilitator superfamily, Monocarboxylate porter (TC 2.A.1.13) family

Tissue Specificity

Strongly expressed in kidney and skeletal muscle and at lower level in placenta and heart.

Database Links

HGNC: 17027

OMIM: 607550

KEGG: hsa:117247

STRING: 9606.ENSP00000357844

UniGene: Hs.591327

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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