SLC35D2 Antibody, FITC conjugated

Datasheet

Code	CSB-PA765728LC01HU
Size	US$166
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) SLC35D2 Polyclonal antibody

Uniprot No.

Q76EJ3

Target Names

SLC35D2

Alternative Names

Fringe connection antibody; HFRC 1 antibody; Hfrc antibody; HFRC1 antibody; Homolog of Fringe connection protein 1 antibody; MGC117215 antibody; MGC142139 antibody; Nucleotide sugar transporter UGTrel8 antibody; S35D2_HUMAN antibody; SLC35D2 antibody; Solute carrier family 35 member D2 antibody; SQV 7L antibody; SQV7-like protein antibody; SQV7L antibody; UDP N acetylglucosamine transporter antibody; UDP-galactose transporter-related protein 8 antibody; UDP-N-acetylglucosamine/UDP-glucose/GDP-mannose transporter antibody; UGTrel 8 antibody; UGTrel8 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human UDP-N-acetylglucosamine/UDP-glucose/GDP-mannose transporter protein (75-146AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

FITC

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

Antiporter transporting nucleotide sugars such as UDP-N-acetylglucosamine (UDP-GlcNAc), UDP-glucose (UDP-Glc) and GDP-mannose (GDP-Man) pooled in the cytosol into the lumen of the Golgi in exchange for the corresponding nucleosides monophosphates (UMP for UDP-sugars and GMP for GDP-sugars). May take part in heparan sulfate synthesis by supplying UDP-Glc-NAc, the donor substrate, and thus be involved in growth factor signaling.

Gene References into Functions

HFRC1 takes part in the synthesis of heparan sulfate by regulating the level of UDP-GlcNAc, a donor substrate for the heparan sulfate synthases PMID: 15082721
HFRC1 was overexpressed in human bronchial epithelial cells and was shown to localize in the Golgi and to enhance the surface expression of N-acetylglucosamine-rich glycans. PMID: 19276090

Subcellular Location

Golgi apparatus membrane; Multi-pass membrane protein.

Protein Families

TPT transporter family, SLC35D subfamily

Tissue Specificity

Highly expressed in heart, kidney, small intestine, placenta, lung and peripheral blood leukocyte. Weakly expressed in skeletal muscle and spleen. Not expressed in brain, colon and thymus.

Database Links

HGNC: 20799

OMIM: 609182

KEGG: hsa:11046

STRING: 9606.ENSP00000253270

UniGene: Hs.494556

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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