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SLC51A Antibody, Biotin conjugated

Datasheet
Code CSB-PA768212LD01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) SLC51A Polyclonal antibody
Uniprot No.
Q86UW1
Target Names
SLC51A
Alternative Names
SLC51A; OSTA; Organic solute transporter subunit alpha; OST-alpha; Solute carrier family 51 subunit alpha
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Organic solute transporter subunit alpha protein (1-48AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Biotin
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
ELISA Protocol
Troubleshooting and FAQs
Antibody FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Essential component of the Ost-alpha/Ost-beta complex, a heterodimer that acts as the intestinal basolateral transporter responsible for bile acid export from enterocytes into portal blood. Efficiently transports the major species of bile acids.
Gene References into Functions
  1. SLC51A expression is significantly upregulated in human masticatory mucosa during wound healing PMID: 28005267
  2. OSTalpha has roles in biological transport and is widely expressed in human tissues PMID: 12719432
  3. human OSTalpha is a glycoprotein that requires interaction with OSTbeta to reach the plasma membrane. However, glycosylation of OSTalpha is not necessary for interaction with the beta subunit or for membrane localization . PMID: 18847488
Subcellular Location
Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein Families
OST-alpha family
Tissue Specificity
Widely expressed with a high expression in ileum. Expressed in testis, colon, liver, small intestine, kidney, ovary and adrenal gland; and at low levels in heart, lung, brain, pituitary, thyroid gland, uterus, prostate, mammary gland and fat.
Database Links

HGNC: 29955

OMIM: 612084

KEGG: hsa:200931

STRING: 9606.ENSP00000296327

UniGene: Hs.630585

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