SLC7A14 Antibody, FITC conjugated

Code CSB-PA844711LC01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) SLC7A14 Polyclonal antibody
Uniprot No.
Target Names
SLC7A14
Alternative Names
SLC7A14 antibody; KIAA1613 antibody; Probable cationic amino acid transporter antibody; Solute carrier family 7 member 14 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Probable cationic amino acid transporter protein (676-771AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
FITC
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
May be involved in arginine transport.
Gene References into Functions
  1. The four SLC7A14 mutations detected herein were unlikely to be pathogenic in this Japanese cohort. The frequency and pathogenicity of SLC7A14 mutations may vary depending on ethnicity, and these mutations may be rare in Japanese patients. PMID: 27028480
  2. Data suggests that cationic transporter SLC7A14 has an important role in retinal development and visual function. PMID: 24670872
  3. A chimera carrying the functional domain of the orphan protein SLC7A14 in the backbone of SLC7A2 mediates trans-stimulated arginine transport. PMID: 22787143
Involvement in disease
Retinitis pigmentosa 68 (RP68)
Subcellular Location
Lysosome membrane; Multi-pass membrane protein. Note=Exhibits a punctated pattern in the cytoplasm, which partially ovelaps with lysosomes.
Protein Families
Amino acid-polyamine-organocation (APC) superfamily, Cationic amino acid transporter (CAT) (TC 2.A.3.3) family
Tissue Specificity
Expressed in skin fibroblasts.
Database Links

HGNC: 29326

OMIM: 615720

KEGG: hsa:57709

STRING: 9606.ENSP00000231706

UniGene: Hs.596660

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