Code | CSB-PA882065LA01HU |
Size | US$166 |
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The SLCO1B3 Antibody (Product code: CSB-PA882065LA01HU) is Non-conjugated. For SLCO1B3 Antibody with conjugates, please check the following table.
Application | Recommended Dilution |
---|---|
IHC | 1:20-1:200 |
IF | 1:50-1:200 |
The SLCO1B3 antibody is generated by immunizing a rabbit with recombinant human SLCO1B3 protein (amino acids 648-695). After that, the resulting polyclonal antibody mixture is extracted from the rabbit's serum and subjected to protein G affinity chromatography purification, which results in a 95% purity level. The purified SLCO1B3 polyclonal antibody is then assessed for its specificity to human SLCO1B3 protein via ELISA and WB assays.
The SLCO1B3 protein, also known as organic anion transporting polypeptide 1B3 (OATP1B3), is a transmembrane protein that is primarily expressed in the liver and other tissues involved in drug metabolisms and elimination, such as the kidney and intestine. In addition to its role in drug transport, SLCO1B3 has been implicated in the regulation of cellular signaling pathways, such as the Akt/mTOR pathway, which is involved in cell proliferation and survival. SLCO1B3 has also been shown to be involved in the regulation of hepatic lipid metabolism.
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