SLCO3A1 Antibody, Biotin conjugated

Datasheet

Code	CSB-PA883432LD01HU
Size	US$166
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) SLCO3A1 Polyclonal antibody

Uniprot No.

Q9UIG8

Target Names

SLCO3A1

Alternative Names

SLCO3A1 antibody; OATP3A1 antibody; OATPD antibody; SLC21A11 antibody; Solute carrier organic anion transporter family member 3A1 antibody; OATP3A1 antibody; Organic anion transporter polypeptide-related protein 3 antibody; OATP-RP3 antibody; OATPRP3 antibody; Organic anion-transporting polypeptide D antibody; OATP-D antibody; PGE1 transporter antibody; Sodium-independent organic anion transporter D antibody; Solute carrier family 21 member 11 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Solute carrier organic anion transporter family member 3A1 protein (439-539AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Biotin

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function

Mediates the Na(+)-independent transport of organic anions such as estrone-3-sulfate. Mediates transport of prostaglandins (PG) E1 and E2, thyroxine (T4), deltorphin II, BQ-123 and vasopressin, but not DPDPE (a derivative of enkephalin lacking an N-terminal tyrosine residue), estrone-3-sulfate, taurocholate, digoxin nor DHEAS.

Gene References into Functions

OATP3A1 functions as a bile acid efflux transporter that is up-regulated as an adaptive response to cholestasis. PMID: 30063921
SLCO3A1, a novel Crohn's disease-associated gene, mediates inflammatory processes in intestinal epithelial cells through NF-kappaB transcription activation. PMID: 24945726
Single nucleotide polymorhpisms of SLCO3A1 were associated with nicotine dependence. PMID: 22377092
OATP-D plays an important role in translocating prostaglandins in specialized tissues and cells. PMID: 14631946
Further evidence is provided for the involvement of OATPs in oligopeptide transport. OATP3A1 variants might be involved in the regulation of extracellular vasopressin concentration in human brain. PMID: 16971491

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Subcellular Location

Cell membrane; Multi-pass membrane protein.

Protein Families

Organo anion transporter (TC 2.A.60) family

Tissue Specificity

Ubiquitous. Highly expressed in spleen and leukocytes. Generally the expression of isoform 1 is higher than that of isoform 2. Isoform 2 is particularly abundant in testis and brain. In testis, isoform 1 is detected in spermatogonia at different stages an

Database Links

HGNC: 10952

OMIM: 612435

KEGG: hsa:28232

STRING: 9606.ENSP00000320634

UniGene: Hs.311187

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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