SLITRK6 Antibody

Code CSB-PA867155LA01HU
Size US$166
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  • Immunohistochemistry of paraffin-embedded human thyroid tissue using CSB-PA867155LA01HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human lung tissue using CSB-PA867155LA01HU at dilution of 1:100

  • Immunofluorescent analysis of HepG2 cells using CSB-PA867155LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) SLITRK6 Polyclonal antibody
Uniprot No.
Target Names
SLITRK6
Alternative Names
4832410J21Rik antibody; DFNMYP antibody; MGC119595 antibody; MGC119596 antibody; MGC119597 antibody; OTTHUMP00000066012 antibody; SLIK6_HUMAN antibody; SLIT and NTRK like family member 6 antibody; SLIT and NTRK like protein 6 antibody; SLIT and NTRK-like protein 6 antibody; Slit and trk like 6 antibody; Slit and trk like gene 6 antibody; SLITRK 6 antibody; Slitrk6 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human SLIT and NTRK-like protein 6 protein (621-821AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The SLITRK6 Antibody (Product code: CSB-PA867155LA01HU) is Non-conjugated. For SLITRK6 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA867155LB01HU SLITRK6 Antibody, HRP conjugated ELISA
FITC CSB-PA867155LC01HU SLITRK6 Antibody, FITC conjugated
Biotin CSB-PA867155LD01HU SLITRK6 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, IHC, IF
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
IF 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Regulator of neurite outgrowth required for normal hearing and vision.
Gene References into Functions
  1. Analysis of two exons of SLITRK6 gene in a Moroccan family identify a novel single deleterious mutation c.696delG, p.Trp232Cysfs*10 at homozygous state in the exon 2 of the SLITRK6, a gene reported to cause deafness and myopia in various populations. PMID: 29551497
  2. Human cytomegalovirus downregulates SLITRK6 expression through IE2. PMID: 27530937
  3. SLITRK6 gene nonsense mutation is associated with progressive auditory neuropathy in humans. PMID: 23946138
  4. SLITRK6 plays a crucial role in the development of normal hearing as well as vision in humans and in mice and that its disruption leads to a syndrome characterized by severe myopia and deafness. PMID: 23543054
Involvement in disease
Deafness and myopia (DFNMYP)
Subcellular Location
Cell membrane; Single-pass type I membrane protein.
Protein Families
SLITRK family
Tissue Specificity
In adult brain, highly expressed in putamen with no expression in cerebral cortex. Expressed in adult and fetal lung and fetal liver. Also expressed at high levels in some brain tumors including medulloblastomas and primitive neuroectodermal tumors.
Database Links

HGNC: 23503

OMIM: 221200

KEGG: hsa:84189

STRING: 9606.ENSP00000383143

UniGene: Hs.525105

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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