SMNDC1 Antibody, FITC conjugated

Datasheet

Code	CSB-PA021840LC01HU
Size	US$166
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) SMNDC1 Polyclonal antibody

Uniprot No.

O75940

Target Names

SMNDC1

Alternative Names

30 kDa splicing factor SMNrp antibody; MGC106917 antibody; MGC112663 antibody; SMN related protein antibody; SMN-related protein antibody; smndc1 antibody; SMNR antibody; SPF30 antibody; SPF30_HUMAN antibody; Splicing factor 30, survival of motor neuron-related antibody; Survival motor neuron domain containing 1 antibody; Survival motor neuron domain containing protein 1 antibody; Survival motor neuron domain-containing protein 1 antibody; Survival of motor neuron related splicing factor 30 antibody; Survival of motor neuron-related-splicing factor 30 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Survival of motor neuron-related-splicing factor 30 protein (1-238AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

FITC

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

Involved in spliceosome assembly.

Gene References into Functions

The results show that SMNDC1 mRNA 5'-UTR forms an intramolecular, parallel G quadruplex structure comprised of three G quartet planes, which is bound specifically by FMRP both in vitro and in mouse brain lysates. PMID: 28612854
The binding specificity and affinity of the Tudor domains of TDRD3, SMN and SPF30 proteins were characterized quantitatively. PMID: 22363433
The structures of SMN and SPF30 Tudor domains bound to symmetric and asymmetric dimethylated arginine (DMA) are presented. PMID: 22101937
U2AF35 and hPrp3 interactions with SPF30 can occur simultaneously, thereby potentially linking 3' splice site recognition with tri-small nuclear ribonucleoprotein addition PMID: 18211889

Subcellular Location

Nucleus speckle. Nucleus, Cajal body.

Protein Families

SMN family

Tissue Specificity

Detected at intermediate levels in skeletal muscle, and at low levels in heart and pancreas.

Database Links

HGNC: 16900

OMIM: 603519

KEGG: hsa:10285

STRING: 9606.ENSP00000358605

UniGene: Hs.632093

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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