SNTB1 Antibody, Biotin conjugated

Code CSB-PA621699LD01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) SNTB1 Polyclonal antibody
Uniprot No.
Target Names
SNTB1
Alternative Names
59 DAP antibody; 59 kDa dystrophin associated protein A1 basic component 1 antibody; 59 kDa dystrophin-associated protein A1 basic component 1 antibody; A1B antibody; Beta 1 syntrophin antibody; Beta-1-syntrophin antibody; BSYN2 antibody; DAPA1B antibody; Dystrophin associated protein A1 59kDa basic component 1 antibody; FLJ22442 antibody; MGC111389 antibody; SNT2 antibody; SNT2B1 antibody; SNTB 1 antibody; Sntb1 antibody; SNTB1_HUMAN antibody; Syntrophin 2 antibody; Syntrophin beta 1 antibody; Syntrophin beta 1 (dystrophin associated protein A1 59kDa basic component 1) antibody; Syntrophin-2 antibody; Tax interaction protein 43 antibody; TIP 43 antibody; TIP-43 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Beta-1-syntrophin protein (51-111AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Biotin
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Adapter protein that binds to and probably organizes the subcellular localization of a variety of membrane proteins. May link various receptors to the actin cytoskeleton and the dystrophin glycoprotein complex.
Gene References into Functions
  1. Our study confirms that the two susceptibility loci ZFHX1B and SNTB1 are associated with moderate to high myopia in a Han Chinese population, as well as in a European population, when both SNPs are combined. PMID: 28848321
  2. SNPs within the SNTB1 gene are associated with increased risk of oral cancer. PMID: 28595731
  3. SNTB1 and MCPH1 are located on chromosome 8, which may be involved in neuroticism, avoidant personality and depression. PMID: 24975899
  4. beta1-syntrophin acts through a class-I PDZ interaction with the C terminus of ABCA1 to regulate the cellular distribution and activity of the transporter PMID: 16192269
Subcellular Location
Cell membrane, sarcolemma; Peripheral membrane protein; Cytoplasmic side. Cell junction. Cytoplasm, cytoskeleton.
Protein Families
Syntrophin family
Tissue Specificity
Ubiquitous.
Database Links

HGNC: 11168

OMIM: 600026

KEGG: hsa:6641

STRING: 9606.ENSP00000378965

UniGene: Hs.46701

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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