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SNX16 Antibody, Biotin conjugated

Datasheet
Code CSB-PA022360LD01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) SNX16 Polyclonal antibody
Uniprot No.
P57768
Target Names
SNX16
Alternative Names
DKFZp666H147 antibody; OTTHUMP00000227313 antibody; OTTHUMP00000227314 antibody; SNX16 antibody; SNX16_HUMAN antibody; Sorting nexin-16 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Sorting nexin-16 protein (1-342AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Biotin
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
ELISA Protocol
Troubleshooting and FAQs
Antibody FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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SNX16 Proteins

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Target Background

Function
May be involved in several stages of intracellular trafficking. Plays a role in protein transport from early to late endosomes. Plays a role in protein transport to the lysosome. Promotes degradation of EGFR after EGF signaling. Plays a role in intracellular transport of vesicular stomatitis virus nucleocapsids from the endosome to the cytoplasm.
Gene References into Functions
  1. SNX16 regulates the recycling trafficking of E-cadherin . SNX16 associates with the cytoplasmic domain of E-cadherin via PPII/alpha2 loop. PMID: 28712807
  2. SNX16 is a sorting nexin that may function in the trafficking of proteins between the early and late endosomal compartments PMID: 12813048
Subcellular Location
Early endosome membrane; Peripheral membrane protein; Cytoplasmic side. Late endosome membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Lysosome.
Protein Families
Sorting nexin family
Tissue Specificity
Detected in placenta, lung, liver,heart and pancreas.
Database Links

HGNC: 14980

OMIM: 614903

KEGG: hsa:64089

STRING: 9606.ENSP00000322652

UniGene: Hs.492121

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