SPACA1 Antibody, HRP conjugated

Code CSB-PA864023LB01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) SPACA1 Polyclonal antibody
Uniprot No.
Target Names
SPACA1
Alternative Names
SACA1_HUMAN antibody; SAMP32 antibody; SPACA1 antibody; Sperm acrosomal membrane-associated protein 32 antibody; Sperm acrosome membrane-associated protein 1 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Sperm acrosome membrane-associated protein 1 protein (30-221AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
HRP
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Plays a role in acrosome expansion and establishment of normal sperm morphology during spermatogenesis. Important for male fertility.
Gene References into Functions
  1. Spaca1 role in male infertility.Distribution of SPACA1 in the sperm affects the outcomes of conventional in vitro fertilization. PMID: 27185107
  2. Human posterior head 20 (hPH20) and homo sapiens sperm acrosome associated 1 (hSPACA1) immunocontraceptive epitopes reduced fertility in male/female mice. PMID: 25209425
  3. SAMP32 was associated with the inner acrosomal membrane and recombinant SAMP32 reacted with serum from an infertile man suggesting that it is isoantigenic PMID: 11870081
Subcellular Location
Cytoplasmic vesicle, secretory vesicle, acrosome inner membrane; Single-pass type I membrane protein.
Tissue Specificity
Testis specific.
Database Links

HGNC: 14967

OMIM: 612739

KEGG: hsa:81833

STRING: 9606.ENSP00000237201

UniGene: Hs.161241

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