SPATS2L Antibody, Biotin conjugated

Code CSB-PA868324HD01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) SPATS2L Polyclonal antibody
Uniprot No.
Target Names
SPATS2L
Alternative Names
DNA polymerase-transactivated protein 6 antibody; DNAPTP6 antibody; SGNP antibody; SPATS2-like protein antibody; Spats2l antibody; Spermatogenesis associated; serine-rich 2-like antibody; SPS2L_HUMAN antibody; Stress granule and nucleolar protein antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human SPATS2-like protein (2-488AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Biotin
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Gene References into Functions
  1. Down-regulation of SPATS2L expression may be related to the etiology of poor sleep quality and chronic abdominal pain. PMID: 25358868
  2. A haplotype of 23 SNPs spanning 131.6 Kb shared by all affected members of 3 linked families with restless legs syndrome was identified. The shared candidate region covers 46.9 Kb over the potassium channel-related gene KCTD18 and exons 10-13 of SPATS2L. PMID: 23054586
  3. Our results suggest that SPATS2L may be an important regulator of beta(2)-adrenergic receptor down-regulation and that there is promise in gaining a better understanding of the biological mechanisms of differential response to beta(2)-agonists through GWAS. PMID: 22792082
  4. SGNP is localized in both the cytoplasm and nucleolus and defines a non-nucleolar compartment containing 5.8S rRNA. Under oxidative stress, SGNP nucleolar localization decreases and it rapidly co-localizes with stress granules. PMID: 19005571
Subcellular Location
Cytoplasm. Nucleus, nucleolus. Note=During oxidative stress as well as UV irradiation, energy deprivation or heat shock, relocalizes to cytoplasmic stress granules. In the nucleus, found in structures lacking NPM1.
Protein Families
SPATS2 family
Database Links

HGNC: 24574

OMIM: 613817

KEGG: hsa:26010

STRING: 9606.ENSP00000351503

UniGene: Hs.120323

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