SRP14 Antibody

Code CSB-PA022673LA01HU
Size US$166
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  • Immunofluorescence staining of HepG2 cells with CSB-PA022673LA01HU at 1:133, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) SRP14 Polyclonal antibody
Uniprot No.
Target Names
SRP14
Alternative Names
18 kDa Alu RNA binding protein antibody; 18 kDa Alu RNA-binding protein antibody; Alu RNA-binding protein, 14-KD subunit antibody; ALURBP antibody; MGC14326 antibody; Signal recognition particle 14 kDa protein antibody; signal recognition particle 14kDa (homologous Alu RNA binding protein) antibody; SRP 14 antibody; SRP14 antibody; SRP14_HUMAN antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Signal recognition particle 14 kDa protein (2-107AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The SRP14 Antibody (Product code: CSB-PA022673LA01HU) is Non-conjugated. For SRP14 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA022673LB01HU SRP14 Antibody, HRP conjugated ELISA
FITC CSB-PA022673LC01HU SRP14 Antibody, FITC conjugated
Biotin CSB-PA022673LD01HU SRP14 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, IF
Recommended Dilution
Application Recommended Dilution
IF 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding.
Gene References into Functions
  1. SRP14 mutant proteins with absence of a peptide elongation delay caused inefficient targeting of preproteins leading to defects in secretion, depletion of proteins in the endogenous membranes, and reduced cell growth. PMID: 18455985
Subcellular Location
Cytoplasm.
Protein Families
SRP14 family
Database Links

HGNC: 11299

OMIM: 600708

KEGG: hsa:6727

STRING: 9606.ENSP00000267884

UniGene: Hs.533732

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