SRP14 Antibody

Datasheet

Code	CSB-PA022673LA01HU
Size	US$166
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Image	Immunofluorescence staining of HepG2 cells with CSB-PA022673LA01HU at 1:133, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) SRP14 Polyclonal antibody

Uniprot No.

P37108

Target Names

SRP14

Alternative Names

18 kDa Alu RNA binding protein antibody; 18 kDa Alu RNA-binding protein antibody; Alu RNA-binding protein, 14-KD subunit antibody; ALURBP antibody; MGC14326 antibody; Signal recognition particle 14 kDa protein antibody; signal recognition particle 14kDa (homologous Alu RNA binding protein) antibody; SRP 14 antibody; SRP14 antibody; SRP14_HUMAN antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Signal recognition particle 14 kDa protein (2-107AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The SRP14 Antibody (Product code: CSB-PA022673LA01HU) is Non-conjugated. For SRP14 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA022673LB01HU	SRP14 Antibody, HRP conjugated	ELISA
FITC	CSB-PA022673LC01HU	SRP14 Antibody, FITC conjugated
Biotin	CSB-PA022673LD01HU	SRP14 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, IF

Recommended Dilution

Application	Recommended Dilution
IF	1:50-1:200

Protocols

ELISA Protocol
Immunofluorescence (IF) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding.

Gene References into Functions

SRP14 mutant proteins with absence of a peptide elongation delay caused inefficient targeting of preproteins leading to defects in secretion, depletion of proteins in the endogenous membranes, and reduced cell growth. PMID: 18455985

Subcellular Location

Cytoplasm.

Protein Families

SRP14 family

Database Links

HGNC: 11299

OMIM: 600708

KEGG: hsa:6727

STRING: 9606.ENSP00000267884

UniGene: Hs.533732

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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