SUSD6 Antibody

Code CSB-PA835675LA01HU
Size US$166
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  • Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA835675LA01HU at dilution of 1:100

  • Immunofluorescent analysis of MCF-7 cells using CSB-PA835675LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) SUSD6 Polyclonal antibody
Uniprot No.
Target Names
SUSD6
Alternative Names
SUSD6 antibody; DRAGO antibody; KIAA0247 antibody; Sushi domain-containing protein 6 antibody; Drug-activated gene overexpressed protein antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Sushi domain-containing protein 6 protein (144-303AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The SUSD6 Antibody (Product code: CSB-PA835675LA01HU) is Non-conjugated. For SUSD6 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA835675LB01HU SUSD6 Antibody, HRP conjugated ELISA
FITC CSB-PA835675LC01HU SUSD6 Antibody, FITC conjugated
Biotin CSB-PA835675LD01HU SUSD6 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, IHC, IF
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
IF 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
May play a role in growth-suppressive activity and cell death. May be involved in the production of chemokine molecules in umbilical vein endothelial cells (HUVECs) cultured in THP1 monocyte LPS-induced medium. Plays a role in preventing tumor onset.
Gene References into Functions
  1. KIAA0247 is a candidate prognostic biomarker and potential therapeutic target in NSCLC. PMID: 29451718
  2. overexpression of KIAA0247 is able to inhibit phosphorylation of AKT and Stat3 in glioma cells, resulting in inactivation of the AKT and Stat3 signaling pathways, this ultimately decreases the expression of PCNA, CyclinD1, Bcl2 and VEGF. PMID: 27893430
  3. DRAGO (drug-activated gene overexpressed) KIAA0247 represents a new p53-dependent gene highly regulated in human cells and whose expression cooperates with p53 in tumor suppressor functions. PMID: 24652652
  4. This is the first description of a linkage between KIAA0247 and colorectal cancer. PMID: 21619678
  5. gene silencing in umbilical vein endothelial cells causes decrease in monocyte chemoattractant protein-1 production during endotoxemia PMID: 20236627

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Subcellular Location
Membrane; Single-pass type I membrane protein.
Database Links

HGNC: 19956

KEGG: hsa:9766

UniGene: Hs.440025

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