SV2B Antibody, FITC conjugated

Code CSB-PA022979LC01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) SV2B Polyclonal antibody
Uniprot No.
Target Names
SV2B
Alternative Names
SV2B antibody; KIAA0735 antibody; Synaptic vesicle glycoprotein 2B antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Synaptic vesicle glycoprotein 2B protein (1-108AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
FITC
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Probably plays a role in the control of regulated secretion in neural and endocrine cells.; (Microbial infection) Receptor for the C.botulinum neurotoxin type A2 (BoNT/A, botA); glycosylation is not essential but enhances the interaction. Probably also serves as a receptor for the closely related C.botulinum neurotoxin type A1.
Gene References into Functions
  1. In classical mesial temporal sclerosis 1A, the expression of SV2 isoforms is altered with a marked decrease of SV2B paralleling synaptic loss. PMID: 23617838
  2. Synaptic vesicle protein 2 binds adenine nucleotides PMID: 18524768
Subcellular Location
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein. Cytoplasmic vesicle, secretory vesicle, acrosome.
Protein Families
Major facilitator superfamily
Database Links

HGNC: 16874

OMIM: 185861

KEGG: hsa:9899

STRING: 9606.ENSP00000332818

UniGene: Hs.21754

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