SWAP70 Antibody

1. Expression of switch-associated protein 70 is associated with lymphocyte activation and reduced disability in multiple sclerosis. PMID: 27495372
2. These data show a key role for SWAP70 as a scaffold for tethering the peripheral actin cage to phagosomes. PMID: 27806292
3. SWAP70 appears to act as a molecular intermediate between vGPCR and endothelial activation. PMID: 25889342
4. SWAP70 may be a target of miR-145, and it might have a potential oncogenic function. PMID: 21360565
5. Detection of SWAP70 antibodies during the attack period might suggest that SWAP70 is involved in Multiple Sclerosis relapse pathogenesis PMID: 22728961
6. The unwinding of the C-terminal alpha-helix could regulate the functions of SWAP-70 at the plasma membrane surface. PMID: 22247562
7. findings suggest that regulation of eosinophil trafficking and migration by SWAP-70 is important for the development of eosinophilic inflammation after allergen exposure PMID: 22210919
8. protein that functions as the only B cell-specific component of an isotype switch recombination PMID: 11726218
9. Overexpression of SWAP-70 altered the actin organization and lamellipodial morphology PMID: 12925760
10. the binding activity of SWAP-70 to non-muscle F-actin is required for membrane ruffling. PMID: 16418221
11. surface expression of SWAP-70 on HIV-1 infected cells as well as PBMCs; SWAP-70 may serve as a marker for T cell differentiation as well as for HIV-1 infection PMID: 16547421
12. SWAP-70 may be involved in regulating migration and invasion of trophoblast cells during the processes of embryonic implantation and placentation in primates. PMID: 17371938

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HGNC: 17070

OMIM: 604762

KEGG: hsa:23075

STRING: 9606.ENSP00000315630

UniGene: Hs.153026