SYNGR1 Antibody

Datasheet

Code	CSB-PA023011ESR2HU
Size	US$166
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) SYNGR1 Polyclonal antibody

Uniprot No.

O43759

Target Names

SYNGR1

Alternative Names

SNG1_HUMAN antibody; Synaptogyrin-1 antibody; Syngr1 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Synaptogyrin-1 protein (1-191AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Tested Applications

ELISA

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function

May play a role in regulated exocytosis. Modulates the localization of synaptophysin/SYP into synaptic-like microvesicles and may therefore play a role in synaptic-like microvesicle formation and/or maturation. Involved in the regulation of short-term and long-term synaptic plasticity.

Gene References into Functions

SYNGR1 was soluble and stable in a variety of mild detergents and multiple biophysical methods confirmed the folded state of the protein. PMID: 22675529
The results of association study support a contribution of SYNGR1 to schizophrenia susceptibility. PMID: 19641478
This research found a novel nonsense mutation (Trp27Ter) in exon 2 of the SYNGR1 gene in a family multiply affected with schizophrenia. And expressed in the brain. PMID: 14732601
Our results support SYNGR1 as a probable susceptibility gene for schizophrenia and bipolar disorder. PMID: 16215643
These mutations were not found in 507 control subjects, suggesting further functional assays are warranted to verify their relevance to the pathogenesis of schizophrenia. PMID: 17049558
A case-control study with synaptogyrin 1 was conducted in 506 bipolar disorder patients and 507 healthy individuals from the Han Chinese population. No association was found in this study. PMID: 19665806

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Subcellular Location

Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein. Melanosome.

Protein Families

Synaptogyrin family

Database Links

HGNC: 11498

OMIM: 603925

KEGG: hsa:9145

STRING: 9606.ENSP00000332287

UniGene: Hs.216226

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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