TAF10 Antibody

Code CSB-PA830634
Size US$166
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Image
  • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA830634(TAF10 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200)
  • The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using CSB-PA830634(TAF10 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200)
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Product Details

Uniprot No.
Target Names
TAF10
Alternative Names
TAF10 antibody; TAF2A antibody; TAF2H antibody; TAFII30 antibody; Transcription initiation factor TFIID subunit 10 antibody; STAF28 antibody; Transcription initiation factor TFIID 30 kDa subunit antibody; TAF(II)30 antibody; TAFII-30 antibody; TAFII30 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse
Immunogen
Synthetic peptide of Human TAF10
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
Antigen affinity purification
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
Liquid
Tested Applications
ELISA,IHC
Recommended Dilution
Application Recommended Dilution
ELISA 1:2000-1:5000
IHC 1:25-1:100
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
TAFs are components of the transcription factor IID (TFIID) complex, PCAF histone acetylase complex and TBP-free TAFII complex (TFTC). TIIFD is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors.
Gene References into Functions
  1. Lysine oxidation of the transcription factor TAF10 by LOXL2 is a controlled protein modification and demonstrates a role for protein oxidation in regulating pluripotency genes. PMID: 25959397
  2. The carboxyl-terminal domain of the largest subunit of RNA polymerase II (pol II) comprises multiple tandem repeats of a heptapeptide. PMID: 20457598
  3. CDKN1C negatively regulates RNA polymerase II C-terminal domain phosphorylation in an E2F1-dependent manner PMID: 20106982
  4. TAF10 can be monomethylated by SET9-mediated methylation. PMID: 15099517
  5. novel role of three mammalian interacting partners in the nuclear localization of TAF10 PMID: 15870280
  6. TAFII30 was required for optimal P4 promoter activity and for the repressive association of estrogen receptor. PMID: 17599049

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Subcellular Location
Nucleus.
Protein Families
TAF10 family
Database Links

HGNC: 11543

OMIM: 600475

KEGG: hsa:6881

STRING: 9606.ENSP00000299424

UniGene: Hs.5158

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