TAF2 Antibody, HRP conjugated

Code CSB-PA747395LB01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) TAF2 Polyclonal antibody
Uniprot No.
Target Names
TAF2
Alternative Names
TAF2 antibody; CIF150 antibody; TAF2B antibody; Transcription initiation factor TFIID subunit 2 antibody; 150 kDa cofactor of initiator function antibody; RNA polymerase II TBP-associated factor subunit B antibody; TBP-associated factor 150 kDa antibody; Transcription initiation factor TFIID 150 kDa subunit antibody; TAF(II)150 antibody; TAFII-150 antibody; TAFII150 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Transcription initiation factor TFIID subunit 2 protein (400-450AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
HRP
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Transcription factor TFIID is one of the general factors required for accurate and regulated initiation by RNA polymerase II. TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. It requires core promoter-specific cofactors for productive transcription stimulation. TAF2 stabilizes TFIID binding to core promoter.
Gene References into Functions
  1. the TAF2-TAF8-TAF10 complex demonstrates that there is a stepwise assembly pathway of nuclear holo-TFIID, regulated by nuclear import of preformed cytoplasmic submodules PMID: 25586196
  2. This study suggested that the Microcephaly thin corpus callosum intellectual disability syndrome is caused by the more conserved mutation p.Thr186Arg, with the second sequence change identified, p.Pro416His. PMID: 24084144
Involvement in disease
Mental retardation, autosomal recessive 40 (MRT40)
Subcellular Location
Nucleus.
Protein Families
TAF2 family
Tissue Specificity
Expressed in all tissues tested.
Database Links

HGNC: 11536

OMIM: 604912

KEGG: hsa:6873

STRING: 9606.ENSP00000367406

UniGene: Hs.122752

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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