TBX15 Antibody, HRP conjugated

Code CSB-PA839414HB01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) TBX15 Polyclonal antibody
Uniprot No.
Target Names
TBX15
Alternative Names
TBX15 antibody; TBX14 antibody; T-box transcription factor TBX15 antibody; T-box protein 15 antibody; T-box transcription factor TBX14 antibody; T-box protein 14 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human T-box transcription factor TBX15 protein (1-496AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
HRP
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Probable transcriptional regulator involved in the development of the skeleton of the limb, vertebral column and head. Acts by controlling the number of mesenchymal precursor cells and chondrocytes.
Gene References into Functions
  1. These studies showed that Tbx15 differentially regulates oxidative and glycolytic metabolism within subpopulations of white adipocytes and preadipocytes. PMID: 28847884
  2. first genome-wide scan for selection in Inuit from Greenland. A region, with a deeply divergent haplotype that is closely related to the sequence in the Denisovan genome contains two genes, WARS2 and TBX15. our study suggests a complex multi-factorial regulation of TBX15 and WARS2. We show that the introgressed region is associated with regional changes in methylation and expression levels PMID: 28007980
  3. TBX15 and NF-kappaB found in this study may be important to understand cancer and development processes. PMID: 27327083
  4. The results indicate the antiapoptotic role of TBX15 in cancer cells, suggesting a contribution of TBX15 in carcinogenesis. PMID: 26216026
  5. Two traits of ear pinna anatomic variation are associated with SNPs in a region overlapping the TBX15 gene. PMID: 26105758
  6. Genes within recently identified loci associated with waist-hip ratio (WHR) exhibit fat depot-specific mRNA expression, which correlates with obesity-related traits. Adipose tissue (AT) mRNA expression of 6 genes (TBX15/WARS2, STAB1, PIGC, ZNRF3, GRB14 PMID: 23670221
  7. We identified homozygosity for a novel nonsense mutation (c.841C>T) in TBX15 predicted to cause a premature stop (p.Arg281*) with truncation of the protein. PMID: 24039145
  8. TBX15 might be involved in the pathophysiology of placental diseases. PMID: 20962579
  9. TBX15 mutations cause craniofacial dysmorphism, hypoplasia of scapula and pelvis, and short stature in Cousin syndrome. PMID: 19068278

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Involvement in disease
Cousin syndrome (COUSS)
Subcellular Location
Nucleus.
Database Links

HGNC: 11594

OMIM: 260660

KEGG: hsa:6913

UniGene: Hs.146196

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