TCIRG1 Antibody, FITC conjugated

Datasheet
Code CSB-PA615690LC01HU
Size US$299
Uniprot No. Q13488
Protocols ELISA Protocol
Immunogen Recombinant Human V-type proton ATPase 116 kDa subunit a isoform 3 protein (76-182AA)
Raised in Rabbit
Species Reactivity Human
Tested Applications ELISA
Relevance Part of the proton channel of V-ATPases (By similarity). Seems to be directly involved in T-cell activation.
Form Liquid
Conjugate FITC
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method >95%, Protein G purified
Isotype IgG
Clonality Polyclonal
Alias V-type proton ATPase 116 kDa subunit a isoform 3 (V-ATPase 116 kDa isoform a3) (Osteoclastic proton pump 116 kDa subunit) (OC-116 kDa) (OC116) (T-cell immune regulator 1) (T-cell immune response cDNA7 protein) (TIRC7) (Vacuolar proton translocating ATPase 116 kDa subunit a isoform 3), TCIRG1, ATP6N1C ATP6V0A3
Immunogen Species Homo sapiens (Human)
Research Area Signal Transduction
Target Names TCIRG1
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Part of the proton channel of V-ATPases (By similarity). Seems to be directly involved in T-cell activation.
Involvement in disease Osteopetrosis, autosomal recessive 1 (OPTB1)
Subcellular Location Membrane, Multi-pass membrane protein
Protein Families V-ATPase 116 kDa subunit family
Tissue Specificity Isoform long is highly expressed in osteoclastomas. Isoform short is highly expressed in thymus.
Database Links

HGNC: 11647

OMIM: 259700

KEGG: hsa:10312

STRING: 9606.ENSP00000265686

UniGene: Hs.495985

Pathway Oxidative Phosphorylation
Synaptic vesicle cycle

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