TCTN2 Antibody

Datasheet

Code	CSB-PA853425ESR2HU
Size	US$166
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Image	Immunohistochemistry of paraffin-embedded human skin tissue using CSB-PA853425ESR2HU at dilution of 1:100
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) TCTN2 Polyclonal antibody

Uniprot No.

Q96GX1

Target Names

TCTN2

Alternative Names

C12orf38 antibody; FLJ12975 antibody; MKS8 antibody; OTTHUMP00000239215 antibody; OTTHUMP00000239216 antibody; Tctn2 antibody; TECT2 antibody; TECT2_HUMAN antibody; Tectonic family member 2 antibody; Tectonic-2 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Tectonic-2 protein (420-670AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Tested Applications

ELISA, IHC

Recommended Dilution

Application	Recommended Dilution
IHC	1:20-1:200

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for hedgehog signaling transduction.

Gene References into Functions

a truncating mutation in TCTN2 linked to Meckel Gruber syndrome was shown. PMID: 21462283
Network building strategy led to the proposal of candidates for new ciliopathy disease genes, leading to the identification of the first human mutations in the Nephronophthisis gene Ataxin10 (ATXN10) and Joubert syndrome gene Tectonic2 (TCTN2). PMID: 21565611

Involvement in disease

Meckel syndrome 8 (MKS8); Joubert syndrome 24 (JBTS24)

Subcellular Location

Membrane; Single-pass type I membrane protein. Cytoplasm, cytoskeleton, cilium basal body.

Protein Families

Tectonic family

Database Links

HGNC: 25774

OMIM: 613846

KEGG: hsa:79867

STRING: 9606.ENSP00000304941

UniGene: Hs.167165

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Email: [email protected]
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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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