TDRD1 Antibody

Datasheet

Code	CSB-PA874834LA01HU
Size	US$166
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Image	Immunohistochemistry of paraffin-embedded human gastric cancer using CSB-PA874834LA01HU at dilution of 1:100 Immunofluorescent analysis of Hela cells using CSB-PA874834LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) TDRD1 Polyclonal antibody

Uniprot No.

Q9BXT4

Target Names

TDRD1

Alternative Names

Cancer/testis antigen 41.1 antibody; CT41.1 antibody; FLJ21082 antibody; MTR 1 antibody; TDRD 1 antibody; tdrd1 antibody; TDRD1_HUMAN antibody; Tudor domain containing 1 antibody; Tudor domain containing protein 1 antibody; Tudor domain-containing protein 1 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Tudor domain-containing protein 1 protein (12-314AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The TDRD1 Antibody (Product code: CSB-PA874834LA01HU) is Non-conjugated. For TDRD1 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA874834LB01HU	TDRD1 Antibody, HRP conjugated	ELISA
FITC	CSB-PA874834LC01HU	TDRD1 Antibody, FITC conjugated
Biotin	CSB-PA874834LD01HU	TDRD1 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, IHC, IF

Recommended Dilution

Application	Recommended Dilution
IHC	1:20-1:200
IF	1:50-1:200

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

Plays a central role during spermatogenesis by participating in the repression transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Required for the localization of Piwi proteins to the meiotic nuage. Involved in the piRNA metabolic process by ensuring the entry of correct transcripts into the normal piRNA pool and limiting the entry of cellular transcripts into the piRNA pathway. May act by allowing the recruitment of piRNA biogenesis or loading factors that ensure the correct entry of transcripts and piRNAs into Piwi proteins.

Gene References into Functions

TDRD1 protein is expressed in the majority of human prostate tumors, but not in normal prostate tissue. PMID: 27272765
the involvement of TDRD1 genetic polymorphisms in piRNA processing genes in the risk of spermatogenic impairment in a Han Chinese population PMID: 27233649
ERG induces epigenetic activation of Tudor domain-containing protein 1 (TDRD1) in ERG rearrangement-positive prostate cancer. PMID: 23555854
TDRD1 is the first identified upregulated direct ERG target gene that is strongly associated with ERG overexpression in primary prostate cancer PMID: 23319146

Subcellular Location

Cytoplasm.

Protein Families

TDRD1 family

Tissue Specificity

Testis and ovary specific. Also expressed in several cancers.

Database Links

HGNC: 11712

OMIM: 605796

KEGG: hsa:56165

STRING: 9606.ENSP00000251864

UniGene: Hs.333132

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Service

Phage Display Service

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Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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