TDRD3 Antibody

Code CSB-PA863996LA01HU
Size US$166
  • Western Blot
    Positive WB detected in: HEK293 whole cell lysate
    All lanes: TDRD3 antibody at 3µg/ml
    Goat polyclonal to rabbit IgG at 1/50000 dilution
    Predicted band size: 74, 84 kDa
    Observed band size: 74 kDa

  • Immunohistochemistry of paraffin-embedded human pancreatic cancer using CSB-PA863996LA01HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human lung cancer using CSB-PA863996LA01HU at dilution of 1:100

The Latest Promotion Free Antibody trial simple
Have Questions? Leave a Message or Start an on-line Chat

Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) TDRD3 Polyclonal antibody
Uniprot No.
Target Names
Alternative Names
4732418C03Rik antibody; 6720468N18 antibody; FLJ21007 antibody; OTTHUMP00000018485 antibody; TDRD 3 antibody; tdrd3 antibody; TDRD3_HUMAN antibody; Tudor domain containing 3 antibody; Tudor domain containing protein 3 antibody; Tudor domain-containing protein 3 antibody
Raised in
Species Reactivity
Recombinant Human Tudor domain-containing protein 3 protein (401-651AA)
Immunogen Species
Homo sapiens (Human)

The TDRD3 Antibody (Product code: CSB-PA863996LA01HU) is Non-conjugated. For TDRD3 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA863996LB01HU TDRD3 Antibody, HRP conjugated ELISA
FITC CSB-PA863996LC01HU TDRD3 Antibody, FITC conjugated
Biotin CSB-PA863996LD01HU TDRD3 Antibody, Biotin conjugated ELISA
Purification Method
>95%, Protein G purified
It differs from different batches. Please contact us to confirm it.
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Tested Applications
Recommended Dilution
Application Recommended Dilution
WB 1:2000-1:5000
IHC 1:20-1:200
Troubleshooting and FAQs
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

 Customer Reviews

There are currently no reviews for this product.

Submit a Review here

Target Background

Scaffolding protein that specifically recognizes and binds dimethylarginine-containing proteins. In nucleus, acts as a coactivator: recognizes and binds asymmetric dimethylation on the core histone tails associated with transcriptional activation (H3R17me2a and H4R3me2a) and recruits proteins at these arginine-methylated loci. In cytoplasm, may play a role in the assembly and/or disassembly of mRNA stress granules and in the regulation of translation of target mRNAs by binding Arg/Gly-rich motifs (GAR) in dimethylarginine-containing proteins.
Gene References into Functions
  1. Structural basis of the interaction between TOP3B and the TDRD3 auxiliary factor has been reported. PMID: 28176834
  2. Top3b proteins from several animals associate with polyribosomes, which are units of mRNA translation, whereas the Top3 homologs from E. coli and yeast lack the association. The Top3b-polyribosome association requires TDRD3, which directly interacts with Top3beta and is present in animals but not bacteria or yeast. PMID: 27257063
  3. The binding specificity and affinity of the Tudor domains of TDRD3, SMN and SPF30 proteins were characterized quantitatively. PMID: 22363433
  4. The TDRD3 is an effector molecule that promotes transcription by binding methylarginine marks on histone tails. PMID: 21172665
  5. Tudor domain of TDRD3 was required for its recruitment to cytoplasmic stress granules. PMID: 18632687
  6. propose a contribution of Tdrd3 to FMRP-mediated translational repression and suggest that the loss of the FMRP-Tdrd3 interaction caused by the I304N mutation might contribute to the pathogenesis of Fragile X syndrome PMID: 18664458

Show More

Hide All

Subcellular Location
Cytoplasm. Nucleus.
Tissue Specificity
Detected in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.
Database Links

HGNC: 20612

OMIM: 614392

KEGG: hsa:81550

STRING: 9606.ENSP00000440190

UniGene: Hs.525061

Call us
301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
7505 Fannin St Ste 610-322 Houston, TX 77054, USA
Join Us with

Leave a message

check code
© 2007-2023 CUSABIO TECHNOLOGY LLC All rights reserved. 鄂ICP备15011166号-1