THOC3 Antibody, FITC conjugated

Code CSB-PA822232LC01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) THOC3 Polyclonal antibody
Uniprot No.
Target Names
THOC3
Alternative Names
hTREX45 antibody; TEX1 homolog antibody; THO complex subunit 3 antibody; Tho3 antibody; THOC3 antibody; THOC3_HUMAN antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human THO complex subunit 3 protein (2-351AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
FITC
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Required for efficient export of polyadenylated RNA and spliced mRNA. Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway. The TREX complex is essential for the export of Kaposi's sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production.
Subcellular Location
Nucleus. Nucleus speckle.
Database Links

HGNC: 19072

OMIM: 606929

KEGG: hsa:84321

STRING: 9606.ENSP00000265097

UniGene: Hs.484227

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