TMEM205 Antibody

Code CSB-PA023799LA01HU
Size US$166
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  • Immunohistochemistry of paraffin-embedded human adrenal gland tissue using CSB-PA023799LA01HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human pancreatic tissue using CSB-PA023799LA01HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) TMEM205 Polyclonal antibody
Uniprot No.
Target Names
TMEM205
Alternative Names
TMEM205; UNQ501/PRO1018; Transmembrane protein 205
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Transmembrane protein 205 protein (104-153AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The TMEM205 Antibody (Product code: CSB-PA023799LA01HU) is Non-conjugated. For TMEM205 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA023799LB01HU TMEM205 Antibody, HRP conjugated ELISA
FITC CSB-PA023799LC01HU TMEM205 Antibody, FITC conjugated
Biotin CSB-PA023799LD01HU TMEM205 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, IHC
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
In cancer cells, plays a role in resistance to the chemotherapeutic agent cisplatin.
Gene References into Functions
  1. The genetic polymorphisms in OCT2, AQP2, AQP9 and TMEM205 may contribute to chemotherapy response in lung cancer patients. PMID: 24643204
  2. Results indicate that a novel mechanism for cisplatin resistance is mediated by TMEM205 overexpression. PMID: 20589834
Subcellular Location
Membrane; Multi-pass membrane protein. Note=Located on cell surface microvilli. In cancer cells, transition in subcellular location from cell surface to intracellular regions correlates the progression of cisplatin resistance.
Protein Families
TMEM205 family
Tissue Specificity
Widely expressed with highest levels in pancreas, followed by adrenal gland, thyroid, liver, mammary gland, prostate, kidney, and retina; lowest levels in skeletal muscle. Overexpressed in cisplatin-resistant cancer cells (at protein level).
Database Links

HGNC: 29631

OMIM: 613771

KEGG: hsa:374882

STRING: 9606.ENSP00000346954

UniGene: Hs.737060

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