TMEM79 Antibody

Code CSB-PA023881LA01HU
Size US$166
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Image
  • IHC image of CSB-PA023881LA01HU diluted at 1:300 and staining in paraffin-embedded human prostate tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) TMEM79 Polyclonal antibody
Uniprot No.
Target Names
TMEM79
Alternative Names
TMEM79; MATT; Transmembrane protein 79; Mattrin
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Transmembrane protein 79 protein (13-127AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The TMEM79 Antibody (Product code: CSB-PA023881LA01HU) is Non-conjugated. For TMEM79 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA023881LB01HU TMEM79 Antibody, HRP conjugated ELISA
FITC CSB-PA023881LC01HU TMEM79 Antibody, FITC conjugated
Biotin CSB-PA023881LD01HU TMEM79 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, IHC
Recommended Dilution
Application Recommended Dilution
IHC 1:200-1:500
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Contributes to the epidermal integrity and skin barrier function. Plays a role in the lamellar granule (LG) secretory system and in the stratum corneum (SC) epithelial cell formation.
Gene References into Functions
  1. Tmem79/Matt is the matted mouse gene and is a predisposing gene for atopic dermatitis in human subjects. PMID: 24084074
Involvement in disease
Defects in TMEM79 may be associated with susceptibility to atopic dermatitis. Atopic dermatitis is a complex, inflammatory disease with multiple alleles at several loci thought to be involved in the pathogenesis. It commonly begins in infancy or early childhood and is characterized by a chronic relapsing form of skin inflammation, a disturbance of epidermal barrier function that culminates in dry skin, and IgE-mediated sensitization to food and environmental allergens. It is manifested by lichenification, excoriation, and crusting, mainly on the flexural surfaces of the elbow and knee.
Subcellular Location
Lysosome. Golgi apparatus, trans-Golgi network. Membrane; Multi-pass membrane protein.
Tissue Specificity
Expressed in the epidermis of the skin. Expressed in epithelial cells of the outermost layer of the stratum granulosum (SG) and hair follicles (at protein level).
Database Links

HGNC: 28196

OMIM: 615531

KEGG: hsa:84283

UniGene: Hs.347408

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