TMEM87B Antibody, FITC conjugated

Code CSB-PA023891LC01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) TMEM87B Polyclonal antibody
Uniprot No.
Target Names
TMEM87B
Alternative Names
TMEM87B; Transmembrane protein 87B
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Transmembrane protein 87B protein (451-554AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
FITC
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
May be involved in retrograde transport from endosomes to the trans-Golgi network (TGN).
Gene References into Functions
  1. Heterozygous loss of FBLN7 and TMEM87B account for some of the clinical features, including cardiac defects and craniofacial abnormalities associated with 2q13 deletion syndrome. PMID: 24694933
Involvement in disease
TMEM87B mutations may be involved in restrictive cardiomyopathy (RCM), a rare non-ischemic myocardial disease. RCM is characterized by restrictive ventricular-filling physiology in the presence of normal or reduced diastolic and/or systolic volumes (of 1 or both ventricles), biatrial enlargement, and normal ventricular wall thickness.
Subcellular Location
Golgi apparatus membrane; Multi-pass membrane protein.
Protein Families
LU7TM family, TMEM87 subfamily
Database Links

HGNC: 25913

OMIM: 617203

KEGG: hsa:84910

STRING: 9606.ENSP00000283206

UniGene: Hs.656298

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