TOB2 Antibody

Datasheet

Code	CSB-PA617901ESR1HU
Size	US$166
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Image	Immunohistochemistry of paraffin-embedded human gastric cancer using CSB-PA617901ESR1HU at dilution of 1:100 Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using CSB-PA617901ESR1HU at dilution of 1:100
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Product Details
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Customer Reviews and Q&A
Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) TOB2 Polyclonal antibody

Uniprot No.

Q14106

Target Names

TOB2

Alternative Names

KIAA1663 antibody; Protein Tob2 antibody; Protein Tob4 antibody; Tob2 antibody; TOB2_HUMAN antibody; TOB4 antibody; Transducer of erbB 2 2 antibody; Transducer of erbB-2 2 antibody; Transducer of ERBB2, 2 antibody; TROB2 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Protein Tob2 protein (1-70AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Tested Applications

ELISA, IHC

Recommended Dilution

Application	Recommended Dilution
IHC	1:20-1:200

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

Anti-proliferative protein inhibits cell cycle progression from the G0/G1 to S phases.

Gene References into Functions

Results show reduced Tob2 expression in primary hepatocellular Carcinoma cells (HCC) and that dysregulation of miR-362 and Tob2 may contribute to HCC malignancy. PMID: 25649327
study identifies miR-378-TOB2-cyclin D1 as a functional module to mediate the cross talk between Myc and Ras signaling in cellular transformation PMID: 21242960
TNFalpha is able to transactivate ErbB-2 and use it as an obligatory downstream signaling molecule in the generation of mitogenic signals. PMID: 19760502
Haploinsufficiency of the MLL and TOB2 genes in lymphoid malignancy. PMID: 19940862

Subcellular Location

Cytoplasm.

Protein Families

BTG family

Tissue Specificity

Ubiquitous.

Database Links

HGNC: 11980

OMIM: 607396

KEGG: hsa:10766

STRING: 9606.ENSP00000331305

UniGene: Hs.474978

Promotions

Transmembrane Protein Questionnaire with Gifts

Email: [email protected]
Distributors Worldwide

Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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