TRAFD1 Antibody

Datasheet

Code	CSB-PA024156LA01HU
Size	US$166
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) TRAFD1 Polyclonal antibody

Uniprot No.

O14545

Target Names

TRAFD1

Alternative Names

FLN29 antibody; FLN29 gene product antibody; Protein FLN29 antibody; TRAD1_HUMAN antibody; TRAF type zinc finger domain containing 1 antibody; TRAF type zinc finger domain containing protein 1 antibody; TRAF-type zinc finger domain-containing protein 1 antibody; TRAFD 1 antibody; TRAFD1 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human TRAF-type zinc finger domain-containing protein 1 protein (2-300AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The TRAFD1 Antibody (Product code: CSB-PA024156LA01HU) is Non-conjugated. For TRAFD1 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA024156LB01HU	TRAFD1 Antibody, HRP conjugated	ELISA
FITC	CSB-PA024156LC01HU	TRAFD1 Antibody, FITC conjugated
Biotin	CSB-PA024156LD01HU	TRAFD1 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Negative feedback regulator that controls excessive innate immune responses. Regulates both Toll-like receptor 4 (TLR4) and DDX58/RIG1-like helicases (RLH) pathways. May inhibit the LTR pathway by direct interaction with TRAF6 and attenuation of NF-kappa-B activation. May negatively regulate the RLH pathway downstream from MAVS and upstream of NF-kappa-B and IRF3.

Gene References into Functions

FLN29 is a new negative feedback regulator of TLR signaling PMID: 16221674
FLN29, in addition to playing a negative regulatory role in the TLR4 signaling pathway, negatively regulates the RIG-I-like helicase signaling pathway at the level of IPS-1/TRAF6 and IPS-1/TRAF3 complexes PMID: 18849341

Database Links

HGNC: 24808

OMIM: 613197

KEGG: hsa:10906

STRING: 9606.ENSP00000257604

UniGene: Hs.5148

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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